头颈部癌症患者放化疗或单纯放疗中营养支持小组早期营养干预的效果。
Effects of early nutritional intervention by a nutritional support team for patients with head and neck cancer undergoing chemoradiotherapy or radiotherapy.
机构信息
Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Asahikawa, Japan.
Department of Innovative Head & Neck Cancer Research and Treatment, Asahikawa Medical University, Asahikawa, Japan.
出版信息
Head Neck. 2021 Feb;43(2):514-519. doi: 10.1002/hed.26502. Epub 2020 Oct 5.
BACKGROUND
We analyzed the effects of early nutritional intervention by a nutritional support team (NST) in patients with head and neck squamous cell carcinoma (HNSCC) undergoing chemoradiotherapy or radiotherapy.
METHODS
This study investigated whether early nutritional interventions by a multidisciplinary NST improve body weight loss, mucositis, serum albumin level, and hospital length of stay.
RESULTS
Sixty-one patients with HNSCC were treated during the study, and 32 patients received NST intervention since admission. The median weight loss rates were 3.3% and 7.3% and grade 3 mucositis was observed in 25.0% and 70.0% of patients in the intervention and nonintervention groups, respectively. In the intervention group, serum albumin level through treatment increased and the hospital length of stay from the end of treatment was shortened.
CONCLUSION
Early nutritional intervention by a multidisciplinary NST improved body weight loss rate, mucositis, albumin level, and hospital length of stay, which might lead to better clinical outcomes.
背景
我们分析了营养支持小组（NST）在接受放化疗或放疗的头颈部鳞状细胞癌（HNSCC）患者中的早期营养干预的效果。
方法
本研究探讨了多学科 NST 的早期营养干预是否改善体重减轻、黏膜炎、血清白蛋白水平和住院时间。
结果
研究期间治疗了 61 例 HNSCC 患者，32 例患者自入院起接受 NST 干预。干预组和非干预组的中位体重减轻率分别为 3.3%和 7.3%，3 级黏膜炎发生率分别为 25.0%和 70.0%。在干预组中，治疗过程中血清白蛋白水平升高，治疗结束后的住院时间缩短。
结论
多学科 NST 的早期营养干预可改善体重减轻率、黏膜炎、白蛋白水平和住院时间，从而改善临床结局。
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