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移动口腔护理应用程序对头颈部癌症患者口腔黏膜炎、疼痛、营养状况和生活质量的影响:一项准实验研究。

Effects of a mobile oral care app on oral mucositis, pain, nutritional status, and quality of life in patients with head and neck cancer: A quasi-experimental study.

机构信息

Department of Nursing, Hsinchu Mackay Memorial Hospital, Hsinchu, Taiwan.

Department of Psychology, Chung Shan Medical University, Clinical Psychological Room, Chung Shan Medical University Hospital, Taichung, Taiwan.

出版信息

Int J Nurs Pract. 2022 Aug;28(4):e13042. doi: 10.1111/ijn.13042. Epub 2022 Feb 27.

Abstract

AIM

The aim of this work is to explore the effectiveness of a mobile app to support oral mucositis care to improve the nutritional status and reduce the occurrence of oral mucositis of patients with head and neck cancer undergoing concurrent chemoradiotherapy.

BACKGROUND

Concurrent chemoradiotherapy is the optimal treatment for head and neck cancer, but oral mucositis and malnutrition are common complications.

DESIGN

Quasi-experimental study using a pre-post design was used in this work.

METHOD

Participants were recruited from a major regional hospital in Taiwan from July 2018 to July 2020. There were 32 participants in each group: the mobile app group (Intervention Group) or routine care (Control Group). The primary outcome measure was Patient-Generated Subjective Global Assessment (PG-SGA). We also collected data on grade of oral mucositis, painNnumeric Rating Scale (NRS), weight loss, haemoglobin (Hb), albumin and quality of life (QoL).

RESULT

The PG-SGA score was significantly lower in the intervention than the control group at all three time points. Hb and albumin decreased less significantly in the intervention than the control group after 2 months. The oral mucositis grade was significantly less severe in the intervention than the control group at all three time points; for the NRS, at T2 and T3.

CONCLUSION

Using the mobile app effectively improved nutritional status, alleviated the side effects, and improved the QoL of head and neck cancer patients with concurrent chemoradiotherapy.

摘要

目的

本研究旨在探讨移动应用程序支持口腔黏膜炎护理的效果,以改善头颈部癌症同步放化疗患者的营养状况,减少口腔黏膜炎的发生。

背景

同步放化疗是头颈部癌症的最佳治疗方法,但口腔黏膜炎和营养不良是常见的并发症。

设计

本研究采用准实验研究,使用前后设计。

方法

参与者来自台湾一家主要的地区医院,招募时间为 2018 年 7 月至 2020 年 7 月。每组有 32 名参与者:移动应用程序组(干预组)或常规护理(对照组)。主要结局测量指标是患者生成的主观整体评估(PG-SGA)。我们还收集了口腔黏膜炎程度、疼痛数字评分量表(NRS)、体重减轻、血红蛋白(Hb)、白蛋白和生活质量(QoL)的数据。

结果

在所有三个时间点,干预组的 PG-SGA 评分均显著低于对照组。干预组在 2 个月后 Hb 和白蛋白的下降幅度明显小于对照组。在所有三个时间点,干预组的口腔黏膜炎严重程度均显著低于对照组;在 T2 和 T3 时,NRS 评分也较低。

结论

使用移动应用程序可有效改善头颈部癌症同步放化疗患者的营养状况,减轻副作用,提高生活质量。

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