Department of Radiology, Tianjin University Tianjin Hospital, Tianjin, China.
Department of Biomedical Engineering, School of Precision Instrument and Optoelectronic Engineering, Tianjin University, Tianjin, China.
Orthop Surg. 2020 Dec;12(6):1718-1725. doi: 10.1111/os.12766. Epub 2020 Oct 4.
To siscuss the clinical significance of the early diagnosis of knee varus and knee osteoarthritis with the combination of negative position and non-negative position and radiography.
One hundred and eighty patients whose femorotibial angles <182° (genu varus positive) measured by X-ray at the weight-bearing position and femorotibial angles ≥182° (genu varus negative) measured by X-ray at the non-weight-bearing position were selected as the sample group from those patients who received knee joint Magnetic resonance imaging (MRI) examination from July 2015 to July 2017. One hundred and eighty patients whose femorotibial angles ≥182° (genu varus negative) measured at both the weight-bearing position and the non-weight-bearing position were selected as the control group. Femorotibial angles of both groups were respectively measured, to respectively compare and analyze the effect of non-weight-bearing false-negative genu varus on the occurrence and severity of injury of medial meniscus and femorotibial articular cartilage. The two groups of patients had no previous history of knee surgery, and no lower limb fracture, inflammation, tumor, metabolic bone disease, or congenital disease.
The weight-bearing tibiofemoral angles of the non-weight-bearing false-negative genu varus group and the negative genu varus group (180.998° ± 0.589°) were lower than the non-weight-bearing tibiofemoral angles (182.501° ± 0.290°), and they were positively correlated (t = -15.048, P < 0.01). The non-weight-bearing knee varus medial meniscus incidence of false- negative group. Medial meniscus injury that occurred in the sample group were 86.7% (156/180) in the anterior horn, 91.7% (165/180) in the body, 88.3% (159/180) in the posterior horn. Medial meniscus injury that occurred in the control group were 46.7% (84 /180) in the anterior horn, 40.6.3% (73/180) in the body, 43.3% (78/180) in the posterior horn. The incidence of degenerative groups, the differences were statistically significant. The incidence and severity of injury were as follows: medial meniscus anterior horn (χ = 41.966, P = 0.000), body (χ = 104.94, P = 0.000), posterior horn (χ = 81.025, P = 0.000). The incidence and severity of medial meniscus injury in the non-weight-bearing knee varus false negative group was higher than in the control group. The non-weight-bearing knee varus false-negative group medial tibiofemoral articular cartilage degeneration rate was 95.0% (171/180); in the control group, medial tibiofemoral articular cartilage degeneration was 65.1% (117/180). Two medial tibiofemoral articular cartilage degeneration incidence were statistically significant. The incidence and severity of injury were as follows: medial tibiofemoral articular cartilage (χ = 50.625, P = 0.000). The incidence and severity of medial tibiofemoral articular cartilage injury in the non-weight-bearing knee varus false negative group was higher than in the control group.
The combined weight-bearing position and non-weight-bearing position imaging examination for diagnosing the non-weight-bearing false-negative genu varus patients at an early date is of significant importance to the early diagnosis and treatment of knee osteoarthritis.
探讨膝关节内翻和膝关节骨关节炎的临床意义,结合阴性和非阴性位置以及影像学检查。
选取 2015 年 7 月至 2017 年 7 月间进行膝关节磁共振成像(MRI)检查的患者,X 射线在负重位时股胫角<182°(阳性膝内翻),X 射线在非负重位时股胫角≥182°(阴性膝内翻)。选择 180 例作为研究组,X 射线在负重位和非负重位时股胫角均≥182°(阴性膝内翻)。分别测量两组患者的股胫角,比较和分析非负重位假阴性膝内翻对内侧半月板和股胫关节软骨损伤的发生和严重程度的影响。两组患者均无膝关节手术史,无下肢骨折、炎症、肿瘤、代谢性骨病或先天性疾病。
非负重位假阴性膝内翻组和阴性膝内翻组的负重位胫股角(180.998°±0.589°)均低于非负重位胫股角(182.501°±0.290°),呈正相关(t=-15.048,P<0.01)。非负重位膝内翻内侧半月板假阴性组发生率。在前角,样本组中发生内侧半月板损伤的有 86.7%(156/180),在体部有 91.7%(165/180),在后角有 88.3%(159/180)。对照组中,前角有 46.7%(84/180),体部有 40.6.3%(73/180),后角有 43.3%(78/180)。退行性组的发生率差异有统计学意义。损伤的发生率和严重程度如下:内侧半月板前角(χ=41.966,P=0.000)、体部(χ=104.94,P=0.000)、后角(χ=81.025,P=0.000)。非负重位膝内翻假阴性组内侧半月板损伤的发生率和严重程度均高于对照组。非负重位膝内翻假阴性组内侧胫骨股关节软骨退变率为 95.0%(171/180);对照组中,内侧胫骨股关节软骨退变率为 65.1%(117/180)。两组内侧胫骨股关节软骨退变发生率差异有统计学意义。损伤的发生率和严重程度如下:内侧胫骨股关节软骨(χ=50.625,P=0.000)。非负重位膝内翻假阴性组内侧胫骨股关节软骨损伤的发生率和严重程度均高于对照组。
早期诊断非负重位假阴性膝内翻患者,结合负重位和非负重位影像学检查,对膝关节骨关节炎的早期诊断和治疗具有重要意义。