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偏振敏感光学相干断层扫描衍生衰减系数图像在滤过泡内部结构可视化中的应用。

Usefulness of Polarization-sensitive Optical Coherence Tomography-derived Attenuation-coefficient Images to Visualize the Internal Structure of the Filtering Bleb.

机构信息

Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Department of Technological Development, Tomey Corporation, Nagoya, Japan.

出版信息

Curr Eye Res. 2021 Apr;46(4):606-609. doi: 10.1080/02713683.2020.1825749. Epub 2020 Oct 4.

Abstract

PURPOSE/AIM OF THE STUDY: Polarization-sensitive anterior-segmental optical coherence tomography (PS-OCT) is useful to evaluate the filtering blebs after trabeculectomy. However, the attenuation phenomenon of OCT signal disturbs the visibility of intra-bleb's structure and distribution of birefringence; a specific parameter of PS-OCT. This study aimed to evaluate the effectiveness of the attenuation-coefficient image of the filtering blebs.

MATERIALS AND METHODS

This study included 25 eyes 6 months after TLE. The attenuation-coefficient image of blebs was calculated from OCT intensity signal information. The contrast level of the image (reflectivity of bleb's surface wall/reflectivity of scleral flap) in both attenuation-coefficient image and intensity image and the height of the bleb's wall were calculated. The improvement extent of contrast was defined as the ratio of contrast (attenuation-coefficient image's contrast/intensity image's contrast). We compared the contrast of attenuation-coefficient image and intensity image and investigated the relationship between improvement extent of contrast and height of bleb's wall.

RESULTS

The contrast of the attenuation-coefficient image (317.7 ± 255.4%) was significantly higher than that of the intensity image (39.1 ± 24.5%) ( < .01) and the improvement extent of contrast was 9.5 ± 4.6 times. Furthermore, there was a positive correlation between the improvement extent of contrast and the height of the bleb's wall (r = 0.44, = .03).

CONCLUSIONS

The contrast of the image at depth of filtering blebs was improved by attenuation-coefficient image. It is suggested that the attenuation-coefficient image may improve the visibility of the structure and distribution of birefringence in the blebs compared to the intensity image.

摘要

目的/研究目的:偏振敏感眼前节光学相干断层扫描(PS-OCT)可用于评估小梁切除术后滤过泡。然而,OCT 信号的衰减现象会干扰 intra-bleb 结构和双折射分布的可见度;这是 PS-OCT 的一个特定参数。本研究旨在评估滤过泡衰减系数图像的有效性。

材料和方法

本研究纳入了 25 只眼,均在小梁切除术后 6 个月。滤过泡的衰减系数图像是从 OCT 强度信号信息中计算得出的。计算了衰减系数图像和强度图像中 bleb 表面壁的对比度水平(bleb 表面壁的反射率/巩膜瓣的反射率)以及 bleb 壁的高度。对比度的改善程度定义为对比度(衰减系数图像的对比度/强度图像的对比度)的比值。我们比较了衰减系数图像和强度图像的对比度,并研究了对比度改善程度与 bleb 壁高度之间的关系。

结果

衰减系数图像的对比度(317.7±255.4%)明显高于强度图像(39.1±24.5%)(<0.01),对比度改善程度为 9.5±4.6 倍。此外,对比度改善程度与 bleb 壁高度之间存在正相关关系(r=0.44,=0.03)。

结论

通过衰减系数图像提高了滤过泡深度处图像的对比度。与强度图像相比,衰减系数图像可能会提高 bleb 中的结构和双折射分布的可见度。

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