Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Department of Technological Development, Tomey Corporation, Nagoya, Japan.
Curr Eye Res. 2021 Apr;46(4):606-609. doi: 10.1080/02713683.2020.1825749. Epub 2020 Oct 4.
PURPOSE/AIM OF THE STUDY: Polarization-sensitive anterior-segmental optical coherence tomography (PS-OCT) is useful to evaluate the filtering blebs after trabeculectomy. However, the attenuation phenomenon of OCT signal disturbs the visibility of intra-bleb's structure and distribution of birefringence; a specific parameter of PS-OCT. This study aimed to evaluate the effectiveness of the attenuation-coefficient image of the filtering blebs.
This study included 25 eyes 6 months after TLE. The attenuation-coefficient image of blebs was calculated from OCT intensity signal information. The contrast level of the image (reflectivity of bleb's surface wall/reflectivity of scleral flap) in both attenuation-coefficient image and intensity image and the height of the bleb's wall were calculated. The improvement extent of contrast was defined as the ratio of contrast (attenuation-coefficient image's contrast/intensity image's contrast). We compared the contrast of attenuation-coefficient image and intensity image and investigated the relationship between improvement extent of contrast and height of bleb's wall.
The contrast of the attenuation-coefficient image (317.7 ± 255.4%) was significantly higher than that of the intensity image (39.1 ± 24.5%) ( < .01) and the improvement extent of contrast was 9.5 ± 4.6 times. Furthermore, there was a positive correlation between the improvement extent of contrast and the height of the bleb's wall (r = 0.44, = .03).
The contrast of the image at depth of filtering blebs was improved by attenuation-coefficient image. It is suggested that the attenuation-coefficient image may improve the visibility of the structure and distribution of birefringence in the blebs compared to the intensity image.
目的/研究目的:偏振敏感眼前节光学相干断层扫描(PS-OCT)可用于评估小梁切除术后滤过泡。然而,OCT 信号的衰减现象会干扰 intra-bleb 结构和双折射分布的可见度;这是 PS-OCT 的一个特定参数。本研究旨在评估滤过泡衰减系数图像的有效性。
本研究纳入了 25 只眼,均在小梁切除术后 6 个月。滤过泡的衰减系数图像是从 OCT 强度信号信息中计算得出的。计算了衰减系数图像和强度图像中 bleb 表面壁的对比度水平(bleb 表面壁的反射率/巩膜瓣的反射率)以及 bleb 壁的高度。对比度的改善程度定义为对比度(衰减系数图像的对比度/强度图像的对比度)的比值。我们比较了衰减系数图像和强度图像的对比度,并研究了对比度改善程度与 bleb 壁高度之间的关系。
衰减系数图像的对比度(317.7±255.4%)明显高于强度图像(39.1±24.5%)(<0.01),对比度改善程度为 9.5±4.6 倍。此外,对比度改善程度与 bleb 壁高度之间存在正相关关系(r=0.44,=0.03)。
通过衰减系数图像提高了滤过泡深度处图像的对比度。与强度图像相比,衰减系数图像可能会提高 bleb 中的结构和双折射分布的可见度。