Department of Urology, Harasanshin Hospital, Fukuoka, Japan.
Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Cancer Invest. 2020 Nov;38(10):559-564. doi: 10.1080/07357907.2020.1833212. Epub 2020 Oct 12.
We analyzed the association between smoking and oncological outcome after radical prostatectomy with neoadjuvant hormonal therapy. This study included men who had undergone radical prostatectomy with neoadjuvant hormonal therapy between 2003 and 2016. We evaluated the association between clinicopathological factors and smoking status as well as the prognostic significance of smoking status in biochemical recurrence. The patients' backgrounds were comparable between smokers and nonsmokers. Smoking status were identified as significant risk factors of biochemical recurrence. Smoking was a risk factor of biochemical recurrence, suggesting that smoking may promote cancer recurrence after surgical treatment combined with hormonal therapy.
我们分析了新辅助激素治疗后根治性前列腺切除术后吸烟与肿瘤学结果之间的关系。这项研究包括 2003 年至 2016 年间接受新辅助激素治疗的根治性前列腺切除术患者。我们评估了临床病理因素与吸烟状况之间的关系，以及吸烟状况对生化复发的预后意义。吸烟者和非吸烟者的患者背景相似。吸烟状况是生化复发的显著危险因素。吸烟是生化复发的危险因素，表明吸烟可能促进手术后联合激素治疗的癌症复发。
