Department of Interventional Radiology, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, People's Republic of China.
Department of Urology Surgery, and The First Affiliated Hospital, Zhengzhou University, Zhengzhou, People's Republic of China.
Cancer Biother Radiopharm. 2022 Nov;37(9):759-765. doi: 10.1089/cbr.2020.4016. Epub 2020 Oct 5.
To evaluate the efficacy of double percutaneous nephrostomy (PCN) combined with ureter occlusion stent for treating cervical cancer complicated with vesicovaginal fistula (VVF). A retrospective analysis was performed for 12 patients with cervical cancer complicated with VVF. Regardless of surgical resection, radiotherapy alone or combined chemoradiotherapy were carried out in all patients. After VVF was diagnosed by gynecological examination, imaging, and cystoscopy, concurrent double PCN and ureter occlusion stent implantation were performed for all patients. All patients successfully received ureter occlusion stent implantation after nephrostomy. The success rate of nephrostomy and stent placement was 100% (12/12). After intervention, urinary fistula immediately disappeared in all patients. One week post-surgery, bilateral hydronephrosis disappeared in 4 patients, and their renal insufficiency and renal function returned to normal. One month after operation, 6 patients with genital eczema or ulcer and 5 patients with urinary tract infection were cured. During follow-up, there were no recurrence in urinary fistula, renal dysfunction, and other complications. Double PCN combined with ureter occlusion stent could effectively treat cervical cancer complicated with VVF hydronephrosis, urinary tract infection, and renal insufficiency and contribute to alleviate all kinds of clinical discomfort.
评价双经皮肾造瘘术(PCN)联合输尿管阻塞支架治疗宫颈癌合并膀胱阴道瘘(VVF)的疗效。对 12 例宫颈癌合并 VVF 患者进行回顾性分析。所有患者均行妇科检查、影像学和膀胱镜检查诊断 VVF 后,无论手术切除与否,均单独行放疗或同步放化疗。确诊 VVF 后,所有患者均行双 PCN 联合输尿管阻塞支架植入术。所有患者均成功接受经皮肾造瘘术后输尿管阻塞支架植入术。肾造瘘和支架置入的成功率为 100%(12/12)。干预后,所有患者的尿瘘立即消失。术后 1 周,4 例患者双侧肾积水消失,肾功能不全和肾功能恢复正常。术后 1 个月,6 例生殖器湿疹或溃疡和 5 例尿路感染患者治愈。随访期间,无尿瘘、肾功能不全等并发症复发。双 PCN 联合输尿管阻塞支架可有效治疗宫颈癌合并 VVF 所致的肾积水、尿路感染和肾功能不全,有助于缓解各种临床不适。