Department of Paediatrics, University of Chieti, Chieti, Italy.
Department of Paediatrics, University of Chieti, Chieti, Italy,
Horm Res Paediatr. 2020;93(4):215-225. doi: 10.1159/000510941. Epub 2020 Oct 5.
Although metabolic syndrome (MetS) in children and adolescents is a frequently discussed topic in the literature, uniform guidelines on its definition and treatment are still lacking. Insulin resistance, central obesity, dyslipidaemia, and hypertension are commonly considered the main components of MetS. The first recommended approach to all these pathological conditions in children and adolescents is lifestyle intervention (diet and physical exercise); however, in some selected cases, a pharmacological or surgical treatment might prove useful for the prevention of metabolic and cardiovascular complications. The aim of this review is to present the more recent evidence about the treatment of the major components of MetS in children and adolescents, focussing on the current recommendations concerning lifestyle changes, available drugs, and bariatric surgery.
虽然儿童和青少年代谢综合征（MetS）是文献中经常讨论的话题，但关于其定义和治疗的统一指南仍缺乏。胰岛素抵抗、中心性肥胖、血脂异常和高血压通常被认为是 MetS 的主要组成部分。对于儿童和青少年的所有这些病理情况，首选的方法是生活方式干预（饮食和体育锻炼）；然而，在某些选定的情况下，药物或手术治疗可能有助于预防代谢和心血管并发症。本文的目的是介绍关于儿童和青少年代谢综合征主要成分治疗的最新证据，重点是关于生活方式改变、现有药物和减肥手术的当前建议。
