Pohlman Robert M, Varghese Tomy
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2023-2026. doi: 10.1109/EMBC44109.2020.9175319.
Microwave ablation has become a common treatment method for liver cancers. Unfortunately, microwave ablation success is correlated with clinician's ability for proper electrode placement and assess ablative margins, requiring accurate imaging of liver tumors and ablated zones. Conventionally, ultrasound and computed tomography are utilized for this purpose, yet both have their respective drawbacks. As an alternate approach, electrode displacement elastography offers promise but is still plagued by decorrelation artifacts reducing lesion depiction and visualization. A recent filtering method, namely dictionary representation, has improved contrast-to-noise ratios without reducing delineation contrast. As a supplement to this recent work, this paper evaluates adaptations on this initial dictionary-learning algorithm and applies them to an EDE phantom and 15 in-vivo patient datasets. Two new adaptations of dictionary representations were evaluated, namely a combined dictionary and magnitude-based dictionary representation. When comparing numerical results, the combined dictionary representation algorithm outperforms the previous developed dictionary representation in signal-to-noise (1.54 dB) and contrast-to-noise (0.67 dB) ratios, while a magnitude dictionary representation produces higher noise levels, but improves visualized strain tensor resolution.
微波消融已成为肝癌的一种常见治疗方法。不幸的是,微波消融的成功率与临床医生正确放置电极和评估消融边缘的能力相关,这需要对肝脏肿瘤和消融区域进行精确成像。传统上,超声和计算机断层扫描用于此目的,但两者都有各自的缺点。作为一种替代方法,电极位移弹性成像有前景,但仍受去相关伪影困扰,降低了病变描绘和可视化效果。一种最近的滤波方法,即字典表示法,提高了对比度噪声比,同时不降低轮廓对比度。作为对这项最新工作的补充,本文评估了对这种初始字典学习算法的改进,并将其应用于一个电极位移弹性成像(EDE)模型和15个体内患者数据集。评估了字典表示法的两种新改进,即组合字典和基于幅值的字典表示法。在比较数值结果时,组合字典表示算法在信噪比(1.54dB)和对比度噪声比(0.67dB)方面优于先前开发的字典表示法,而幅值字典表示法产生更高的噪声水平,但提高了可视化应变张量分辨率。