生理条件下尺寸可控的巨型囊泡的制备
Preparation of Size-controlled Giant Vesicles Under Physiological Conditions.
作者信息
Peng Zugui, Kanno Shoichiro, Shimba Kenta, Miyamoto Yoshitaka, Yagi Tohru
出版信息
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2198-2201. doi: 10.1109/EMBC44109.2020.9175877.
Abstract
Giant vesicles (GVs) are model cell membranes that function as tools for the study of cell membrane properties. Recently, researchers have been calling for GVs of specific sizes for use in studies with precise needs. In this paper, we report a method of forming GVs of specific sizes by using an agarose-swelling approach. The resulting GVs had a narrow size distribution and were successfully formed under physiological conditions.
摘要
巨型囊泡（GVs）是作为研究细胞膜特性工具的模型细胞膜。最近，研究人员一直呼吁获得特定大小的巨型囊泡，用于有精确需求的研究。在本文中，我们报告了一种通过琼脂糖膨胀法形成特定大小巨型囊泡的方法。所得到的巨型囊泡具有狭窄的尺寸分布，并且在生理条件下成功形成。
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