P M Nabeel, Manoj Rahul, V V Abhidev, Joseph Jayaraj, Kiran V Raj, Sivaprakasam Mohanasankar
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2752-2755. doi: 10.1109/EMBC44109.2020.9175733.
Intervention in the early stages of cardiovascular and kidney diseases is proven to be more effective in preventing disease progression. Large artery stiffness measurement can be a potential early predictor of future risks. The purpose of the study reported in this work was to demonstrate the feasibility of our ARTSENS Pen device as a high-throughput vascular screening tool for risk assessment. The study was performed during a medical camp conducted for awareness and early-stage detection of kidney diseases. Screening procedures included biosample tests and blood pressure measurements. Alongside, various clinically relevant measures of the arterial stiffness were evaluated using the ARTSENS Pen, by measuring vessel wall dynamics via our proprietary image-free ultrasound algorithms. Stiffness measurement from the left common carotid artery on 85 participants could be completed within 4 hours, employing two units of ARTSENS Pen; this also includes time taken for all the procedures enlisted in the study protocol. The associations of carotid stiffness indices with age-, gender-, and risk factor-dependent variations were established.
事实证明，在心血管疾病和肾脏疾病的早期阶段进行干预，对于预防疾病进展更为有效。大动脉僵硬度测量可能是未来风险的一个潜在早期预测指标。本文所报道研究的目的是证明我们的ARTSENS Pen设备作为一种用于风险评估的高通量血管筛查工具的可行性。该研究是在一个为提高肾脏疾病认知和早期检测而举办的医疗营期间进行的。筛查程序包括生物样本检测和血压测量。与此同时，使用ARTSENS Pen通过我们专有的无图像超声算法测量血管壁动力学，对各种与动脉僵硬度相关的临床指标进行了评估。使用两台ARTSENS Pen设备，85名参与者的左颈总动脉僵硬度测量可在4小时内完成；这还包括研究方案中列出的所有程序所需的时间。确定了颈动脉僵硬度指数与年龄、性别和风险因素相关变化之间的关联。
