Keloth Sana M, Radcliffe Peter Jones, Raghav Sanjay, Arjunan Sridhar P, Kumar Dinesh
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:3158-3161. doi: 10.1109/EMBC44109.2020.9176490.
Surface electromyography (sEMG) of the lower limb muscles has been proposed to evaluate motor dysfunctions in Parkinson's disease (PD) patients. Variability in the sEMG could be used as an indicator of poor muscle coordination, but previous studies have reported conflicting results. This study has examined the variability of muscle using the coefficients of variance of Tibialis anterior (TA) and Medial gastrocnemius (MG) lower limb muscles for 24 PD, 24 age matched controls (CO), and 24 young controls (YC), during different phases of the gait cycle. The gait intervals were measured using the inertial measurement unit (IMU). We observed a statistically significant difference between PD and control for the variability of lower limb muscle when comparing the sub-phases of the gait. It was also found that the difference was more pronounced for the TA muscle.
下肢肌肉的表面肌电图（sEMG）已被用于评估帕金森病（PD）患者的运动功能障碍。sEMG的变异性可作为肌肉协调性差的指标，但先前的研究报告结果相互矛盾。本研究通过测量24例PD患者、24例年龄匹配的对照组（CO）和24例年轻对照组（YC）在步态周期不同阶段胫骨前肌（TA）和腓肠肌内侧头（MG）下肢肌肉的变异系数，研究了肌肉的变异性。使用惯性测量单元（IMU）测量步态间隔。在比较步态子阶段时，我们观察到PD组和对照组在下肢肌肉变异性方面存在统计学显著差异。还发现，TA肌肉的差异更为明显。
