超声引导下泡沫硬化疗法治疗后静脉血栓栓塞症。
Venous thromboembolism after ultrasound guided foam sclerotherapy.
机构信息
Spaço Vascular, São Paulo, Brazil.
ABFL - Brazilian Association of Phlebology and Lymphology, São Paulo, Brazil.
出版信息
Phlebology. 2021 Apr;36(3):233-239. doi: 10.1177/0268355520957202. Epub 2020 Oct 6.
OBJECTIVE
To analyze prevalence of venous thromboembolism (VTE) after ultrasound guided foam sclerotherapy.
METHOD
Clinical retrospective study with patients treated from 2004 to 2014. Charts with incomplete data and follow-up less than 60 days were excluded. Polidocanol foam (Tessari method) was used. The primary outcome was the prevalence of VTE and the secondary were possible risk factors. Chi-square test and Marascuillo prodecure were applied at a significance level of 5%.
RESULTS
2,616 patients were included with 4,712 lower limbs treated. The mean age was 50.7±0.86, in majority female, 83.7%. VTE occurred in 0.49% (pulmonary embolism 0,3%) in a mean time of 44.0±42.2 days. Male gender, personal or family history of phlebitis or DVT and high caliber varicose veins were significantly associated to VTE.
CONCLUSION
incidence of VTE is low, male gender, personal or family history of VTE and caliber of varicose veins greater than 7 mm increased the risk.
目的
分析超声引导下泡沫硬化疗法后静脉血栓栓塞症（VTE）的发生率。
方法
对 2004 年至 2014 年接受治疗的患者进行临床回顾性研究。排除数据不完整和随访时间少于 60 天的病历。使用聚多卡醇泡沫（Tessari 法）。主要结局是 VTE 的发生率，次要结局是可能的危险因素。应用卡方检验和 Marascuillo 程序，显著性水平为 5%。
结果
共纳入 2616 例患者，4712 条下肢接受治疗。平均年龄为 50.7±0.86 岁，其中女性占 83.7%。VTE 的发生率为 0.49%（肺栓塞 0，3%），平均发生时间为 44.0±42.2 天。男性、个人或家族静脉炎或 DVT 病史以及大口径静脉曲张与 VTE 显著相关。
结论
VTE 的发生率较低，男性、个人或家族 VTE 病史以及静脉曲张直径大于 7 毫米会增加风险。
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