The enterohepatic circulation of conjugated bile acids in healthy man: quantitative description and functions.
作者信息
Hofmann A F
出版信息
Expos Annu Biochim Med. 1977;33:69-86.
PMID:330215
Abstract
A multicompartmental model describing the enterohepatic circulation of conjugated bile acids in man under steady-state conditions is proposed. The model encompasses conjugation; deconjugation and reconjugation; dehydroxylation; sulfation, desulfation and resulfation; dehydrogenation; and stereoselective rehydrogenation. A dynamic description of the enterohepatic circulation and a brief description of bile acid functions in health and dysfunctions in disease are also discussed.
摘要
相似文献
1
The enterohepatic circulation of conjugated bile acids in healthy man: quantitative description and functions.
Expos Annu Biochim Med. 1977;33:69-86.
2
Bile salts in health and disease.健康与疾病中的胆盐。
Mich Med. 1972 Oct;71(30):865-9.
3
4
5
Role of gallbladder in gallstone formation.胆囊在胆结石形成中的作用。
Acta Chir Scand. 1974;140(1):45-9.
6
7
Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man.人体胆汁酸代谢和肠肝循环的生理药代动力学模型的描述与模拟。健康人体内的胆酸。
J Clin Invest. 1983 Apr;71(4):1003-22. doi: 10.1172/jci110828.
8
Effect of oral chenodeoxycholic acid on bile acid kinetics and biliary lipid composition in women with cholelithiasis.口服鹅去氧胆酸对胆石症女性胆汁酸动力学和胆汁脂质成分的影响。
J Clin Invest. 1973 Nov;52(11):2809-21. doi: 10.1172/JCI107477.
9
Increased sulfation of lithocholate in patients with cholesterol gallstones during chenodeoxycholate treatment.鹅去氧胆酸治疗期间胆固醇结石患者中石胆酸硫酸化增加。
Digestion. 1975;12(2):105-10. doi: 10.1159/000197660.
10
Metabolism of lithocholate in healthy man. II. Enterohepatic circulation.健康人石胆酸盐的代谢。II. 肠肝循环。
Gastroenterology. 1975 Jul;69(1):67-76.
引用本文的文献
1
Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man.人体胆汁酸代谢和肠肝循环的生理药代动力学模型的描述与模拟。健康人体内的胆酸。
J Clin Invest. 1983 Apr;71(4):1003-22. doi: 10.1172/jci110828.
Zotero 插件