The Division of Cardiovascular Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Cardiovascular Research Foundation, New York, NY, USA.
Trends Cardiovasc Med. 2021 Oct;31(7):427-432. doi: 10.1016/j.tcm.2020.09.004. Epub 2020 Oct 3.
Despite ongoing advances in the treatment of heart failure, overall symptom burden remains high. Underlying the primary symptom of dyspnea are often elevations in left atrial pressures, which occur across the spectrum of heart failure subgroups. Current therapies do not directly address improvements in left atrial pressures; however, passive left atrial decompression may offer a new avenue to treat heart failure. New technologies are currently being evaluated in clinical testing and may offer a novel therapeutic approach to heart failure.
尽管心力衰竭的治疗不断取得进展,但整体症状负担仍然很高。呼吸困难的主要症状背后通常是左心房压力升高,这种情况发生在心力衰竭亚组的整个范围内。目前的治疗方法并不能直接解决左心房压力的改善问题;然而,被动左心房减压可能为治疗心力衰竭提供新的途径。新技术目前正在临床测试中进行评估,可能为心力衰竭提供一种新的治疗方法。