Yui Y, Aoyama T, Murohara R, Takatsu Y, Susawa T, Yui N, Hattori R, Kawai C
Jpn Circ J. 1987 Apr;51(4):462-4. doi: 10.1253/jcj.51.462.
Human serum or plasma contains two factors which regulate PGI2 metabolism. The one is "PGI2-synthesis stimulating factor" which stimulates PGI2 synthesis in the vessel wall. The other is "PGI2-stabilizing factor" which stabilizes PGI2 in the blood. In the very early phase of acute myocardial infarction, the serum levels of these two factors were significantly reduced, which may be related to the thrombus formation in the coronary artery in acute myocardial infarction.
人血清或血浆中含有两种调节前列环素（PGI2）代谢的因子。一种是“PGI2合成刺激因子”，可刺激血管壁中PGI2的合成。另一种是“PGI2稳定因子”，可使血液中的PGI2稳定。在急性心肌梗死的极早期，这两种因子的血清水平显著降低，这可能与急性心肌梗死时冠状动脉内血栓形成有关。
