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新冠疫情期间关闭学校、关闭酒吧和佩戴口罩的强烈影响:一项简单且具启发性分析的结果

Strong impact of closing schools, closing bars and wearing masks during the Covid-19 pandemic: results from a simple and revealing analysis.

作者信息

Matzinger Polly, Skinner Jeff

出版信息

medRxiv. 2020 Sep 28:2020.09.26.20202457. doi: 10.1101/2020.09.26.20202457.

DOI:10.1101/2020.09.26.20202457
PMID:33024976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7536875/
Abstract

Many complex mathematical and epidemiological methods have been used to model the Covid-19 pandemic. Among other results from these models has been the view that closing schools had little impact on infection rates in several countries1. We took a different approach. Making one assumption, we simply plotted cases, hospitalizations and deaths, on a log2 Y axis and a linear date-based X axis, and analyzed them using segmented regression, a powerful method that has largely been overlooked during this pandemic. Here we show that the data fit straight lines with correlation coefficients ranging from 92% - 99%, and that these lines broke at interesting intervals, revealing that school closings dropped infection rates in half, lockdowns dropped the rates 3 to 4 fold, and other actions (such as closing bars and mandating masks) brought the rates even further down. Hospitalizations and deaths paralleled cases, with lags of three to ten days. The graphs, which are easy to read, reveal changes in infection rates that are not obvious using other graphing methods, and have several implications for modeling and policy development during this and future pandemics. Overall, other than full lockdowns, three interventions had the most impact: closing schools, closing bars and wearing masks: a message easily understood by the public.

摘要

许多复杂的数学和流行病学方法已被用于对新冠疫情进行建模。这些模型得出的其他结果包括,在一些国家关闭学校对感染率影响甚微。我们采用了不同的方法。基于一个假设,我们简单地将病例数、住院数和死亡数绘制在以2为底的对数Y轴和基于日期的线性X轴上,并使用分段回归进行分析,这是一种强大的方法,但在这场疫情期间基本上被忽视了。在此我们表明,数据拟合的直线相关系数在92%至99%之间,并且这些直线在有趣的时间间隔处出现断点,这表明关闭学校使感染率减半,封锁使感染率下降了3至4倍,而其他措施(如关闭酒吧和强制佩戴口罩)使感染率进一步下降。住院数和死亡数与病例数平行,滞后三到十天。这些图表易于解读,揭示了使用其他绘图方法不明显的感染率变化,并且对此次及未来疫情期间的建模和政策制定有若干启示。总体而言,除全面封锁外,三项干预措施影响最大:关闭学校、关闭酒吧和佩戴口罩,这是公众很容易理解的信息。

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