Eichhorn T, Schroeder H G, Glanz H, Schwerk W B
Laryngol Rhinol Otol (Stuttg). 1987 May;66(5):266-74.
During a period of 2 1/2 years palpation and high-resolution real-time sonography were carried out in 83 non-selected patients with head and neck carcinomas to diagnose metastatic involvement of cervical lymph nodes. The findings were compared with the results of the microscopic examination of the lymph nodes from the neck dissection specimen. Sonography is characterized by a high sensitivity in the detection of lymph node metastases. The relatively low specificity of this method proves that many enlarged but not metastatically involved lymph nodes are also displayed by ultrasound. Although there are no specific echomorphological criteria permitting a reliable identification of lymph node metastases, their sonographic visibility cannot be determined only by the size of the lymph node. Lymph node metastases less than 1.5 cm in diameter, in particular, can be detected more often by ultrasound than by palpation. Therefore, it can be presumed that pathological transformations besides the reactive hyperplasia occurring during metastatic involvement will also influence the echographic representation of lymph nodes. The accuracy data of other methods used for detecting lymph node metastases (computed tomography and lymphoscintigraphy) were compiled from the literature and compared with those of palpation in more than 5000 patients. Basing on our experiences with sonography in this field we tried to assess the chances and limitations of ultrasound in the pretherapeutic diagnosis of cervical lymph node metastases.
在2年半的时间里,对83例未经挑选的头颈部癌患者进行了触诊和高分辨率实时超声检查,以诊断颈部淋巴结的转移情况。将检查结果与颈部清扫标本中淋巴结的显微镜检查结果进行了比较。超声检查的特点是在检测淋巴结转移方面具有高敏感性。该方法相对较低的特异性表明,许多肿大但未发生转移的淋巴结也会在超声检查中显示出来。虽然没有特定的超声形态学标准能够可靠地识别淋巴结转移,但它们在超声下的可见性不能仅由淋巴结的大小来决定。特别是直径小于1.5 cm的淋巴结转移,超声检查比触诊更常能检测到。因此,可以推测,除了转移过程中出现的反应性增生外,病理改变也会影响淋巴结的超声表现。用于检测淋巴结转移的其他方法(计算机断层扫描和淋巴闪烁造影)的准确性数据是从文献中收集的,并与5000多名患者的触诊结果进行了比较。基于我们在该领域超声检查的经验,我们试图评估超声在颈部淋巴结转移术前诊断中的机会和局限性。