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The ten reasons why corticosteroid therapy reduces mortality in severe COVID-19.

作者信息

Arabi Yaseen M, Chrousos George P, Meduri G Umberto

机构信息

Intensive Care Department, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia.

University Research Institute of Maternal and Child Health and Precision Medicine, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

Intensive Care Med. 2020 Nov;46(11):2067-2070. doi: 10.1007/s00134-020-06223-y. Epub 2020 Oct 7.

DOI:10.1007/s00134-020-06223-y
PMID:33026460
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7538533/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f599/7538533/8c2d87e111f9/134_2020_6223_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f599/7538533/8c2d87e111f9/134_2020_6223_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f599/7538533/8c2d87e111f9/134_2020_6223_Fig1_HTML.jpg

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本文引用的文献

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Re-analysis of Single Cell Transcriptome Reveals That the NR3C1-CXCL8-Neutrophil Axis Determines the Severity of COVID-19.单细胞转录组再分析显示 NR3C1-CXCL8-中性粒细胞轴决定了 COVID-19 的严重程度。
Front Immunol. 2020 Aug 28;11:2145. doi: 10.3389/fimmu.2020.02145. eCollection 2020.
2
A living WHO guideline on drugs for covid-19.关于新冠病毒药物的世界卫生组织实用指南。
BMJ. 2020 Sep 4;370:m3379. doi: 10.1136/bmj.m3379.
3
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
皮质类固醇的疗效可能取决于在重症 COVID-19 中的使用时间。
Korean J Intern Med. 2023 May;38(3):382-392. doi: 10.3904/kjim.2022.201. Epub 2023 Apr 11.
4
An Integrated Radiologic-Pathologic Understanding of COVID-19 Pneumonia.新型冠状病毒肺炎的放射-病理综合理解
Radiology. 2023 Feb;306(2):e222600. doi: 10.1148/radiol.222600. Epub 2023 Jan 17.
5
Early dexamethasone use as a protective measure in non-mechanically ventilated critically ill patients with COVID-19: a multicenter, cohort study.COVID-19 非机械通气危重症患者中早期使用地塞米松作为保护措施的多中心队列研究。
Sci Rep. 2022 Jun 13;12(1):9766. doi: 10.1038/s41598-022-13239-5.
6
Usage of compromised lung volume in monitoring steroid therapy on severe COVID-19.使用受损肺容积监测重症 COVID-19 的类固醇治疗。
Respir Res. 2022 Apr 29;23(1):105. doi: 10.1186/s12931-022-02025-6.
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Remdesivir plus Dexamethasone in COVID-19: A cohort study of severe patients requiring high flow oxygen therapy or non-invasive ventilation.瑞德西韦联合地塞米松治疗 COVID-19:需要高流量氧疗或无创通气的重症患者的队列研究。
PLoS One. 2022 Apr 28;17(4):e0267038. doi: 10.1371/journal.pone.0267038. eCollection 2022.
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