Van Metre T E
N Engl Reg Allergy Proc. 1987 Jan-Feb;8(1):17-21. doi: 10.2500/108854187779045367.
The science of allergy and immunology has advanced to the point where effective procedures for diagnosis and treatment of food allergy can be proven to be effective. Currently available procedures of proven effectiveness are sufficiently satisfactory for diagnosis and treatment of food allergy so that ones of unproven effectiveness should not be employed in routine fashion, but rather should be considered experimental and reserved for use with informed consent in controlled trials which have been approved for safety and scientific merit by competent institutional review boards. Leucocytoxic testing, intracutaneous and subcutaneous provocation and neutralization, and sublingual provocation and neutralization are unproven procedures and should be reserved for experimental use only.
过敏与免疫学已经发展到能够证明食物过敏诊断和治疗的有效程序有效的程度。目前已证实有效的程序对于食物过敏的诊断和治疗已经足够令人满意，因此未经证实有效的程序不应常规使用，而应被视为实验性的，仅在经过主管机构审查委员会批准其安全性和科学价值的对照试验中，在获得知情同意的情况下使用。白细胞毒性检测、皮内和皮下激发及中和试验，以及舌下激发及中和试验都是未经证实的程序，应仅保留用于实验用途。
