Meyran M, Buisson Y, Saliou P, Levagueresse R, Santiago M, Thabaut A
Pathol Biol (Paris). 1987 May;35(5):457-60.
The minimal inhibiting concentrations (MIC) of 5 aminosids have been determined by the microdilution method in liquid medium of 4,582 bacterial strains isolated from various pathological samples: 1,039 Staphylococcus, 2,629 Enterobacteria, 759 Pseudomonas and 155 Acinetobacter. The phenotype of resistance has been defined for each strain by listing the antibiotics for which a resistance was observed. The frequencies of the bacterial resistances varied according to the aminosid (gentamicin, sisomicin, tobramycin, netilmicin and amikacin) and to the species studied. For the bacterial species studied, these frequencies of resistance to the aminosid family of antibiotic were weaker in the military hospitals in the district of Paris, than in different civil hospitals where similar studies were conducted.
通过微量稀释法在液体培养基中测定了从各种病理样本中分离出的4582株细菌对5种氨基糖苷类药物的最低抑菌浓度（MIC）：1039株葡萄球菌、2629株肠杆菌、759株假单胞菌和155株不动杆菌。通过列出观察到耐药性的抗生素来确定每个菌株的耐药表型。细菌耐药频率因氨基糖苷类药物（庆大霉素、西索米星、妥布霉素、奈替米星和阿米卡星）和所研究的菌种而异。在所研究的细菌种类中，巴黎地区军事医院对氨基糖苷类抗生素家族的耐药频率低于进行类似研究的不同民事医院。
