Jaffé G
J Int Med Res. 1977;5(3):195-8. doi: 10.1177/030006057700500309.
A multicentre trial was conducted to compare Lomotil and Imodium in the treatment of acute non-specific diarrhoea in general practice. A total of eighty-three patients contributed to the study and were randomly allocated to one of the two treatments. No statistically significant differences were found betwwen the drugs in their efficacy and speed of action in alleviating diarrhoea or in their palliative effect on nausea/vomiting and abdominal pain when present.
开展了一项多中心试验,以比较洛哌丁胺和易蒙停在全科医疗中治疗急性非特异性腹泻的效果。共有83名患者参与了该研究,并被随机分配至两种治疗方法之一。在缓解腹泻的疗效和起效速度方面,以及在对恶心/呕吐和腹痛(若存在)的缓解作用方面,两种药物之间未发现具有统计学意义的差异。