Rahemi Karizaki S, Alamdaran S A, Bonakdaran S, Morovatdar N, Jafarain A H, Sharifi Hadad A, Hadadzade A
Mashhad University of Medical Sciences, Omid Hospital - Radiology - Mashhad, Iran.
Mashhad University of Medical Sciences, Omid Hospital - Endocrine Research Center-Ghaem Hospital, Mashhad, Iran.
Acta Endocrinol (Buchar). 2020 Apr-Jun;16(2):199-207. doi: 10.4183/aeb.2020.199.
The present study aimed to introduce a new formula for classification of nodules in TI-RADS and describe ultrasonography features of benign and malignant thyroid nodules.
This study was conducted on thyroid mass in 1033 patients. The incidence of malignancy for thyroid nodules was determined by selecting malignancy coefficients. Then the patients were first classified using conventional TI-RADS classification criteria and once again according to a new proposed formula.
Among ultrasonography features of thyroid nodules, the irregular shape (46.7%), unclear margin (47.3%), extension to the capsule (irregular and infiltrative margin) (85%), the marked hypo-echoic nodules (63.8%), micro-calcification (49%), and to have vertical axis (74.0%) were associated with high incidence of malignancy.
According to the proposed new formula for TI-RADS, there are four coefficients of 7, 3, 1 and 0 for incidence of malignancy of each one of ultrasound findings that help to standardization and unifying of TI-RADS classification. The incidence of malignancy in TI-RADS classification according to the new proposed formula was achieved as follows: group 2: 0.0%, group 3: 0.7%, groups 4a, 4b, 4c: 16.7%, 43.4%, 68.5%, and group 5: 95.2%, respectively.
本研究旨在引入一种用于TI-RADS中结节分类的新公式，并描述良恶性甲状腺结节的超声特征。
本研究对1033例患者的甲状腺肿物进行。通过选择恶性系数来确定甲状腺结节的恶性发生率。然后首先使用传统的TI-RADS分类标准对患者进行分类，再根据新提出的公式进行一次分类。
在甲状腺结节的超声特征中，形状不规则（46.7%）、边界不清（47.3%）、向包膜延伸（边界不规则和浸润性）（85%）、显著低回声结节（63.8%）、微钙化（49%）以及纵横比＞1（74.0%）与高恶性发生率相关。
根据所提出的TI-RADS新公式，每个超声表现的恶性发生率有7、3、1和0四个系数，这有助于TI-RADS分类的标准化和统一。根据新提出的公式，TI-RADS分类中的恶性发生率如下：2类：0.0%，3类：0.7%，4a、4b、4c类：16.7%、43.4%、68.5%，5类：95.2%。
