Muayqil Taim Abdullah, Tarakji Ahmad Raed, Khattab Abdullah Mohammad, Balbaid Nasser Talal, Al-Dawalibi Ahmad Mohedeen, Alqarni Sami Ahmed, Hazazi Reema Ali, Alanazy Mohammed H
Neurology Unit, Department of Internal Medicine, College of Medicine, King Saud University, PO Box 7805 (38) Riyadh 11472, Saudi Arabia.
Nephrology Unit, Department of Internal Medicine, College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia.
Behav Neurol. 2020 Sep 22;2020:7963837. doi: 10.1155/2020/7963837. eCollection 2020.
The clock drawing test (CDT) is frequently used to detect changes in cognition. Multiple scales of varying length have been published to assess performance. The aim of this study is to compare the CDT performance measured by three scales among a sample of nondemented patients on renal dialysis and identify the variables that affect performance. . This is a cross-sectional study performed at the dialysis unit at King Saud University Medical City. Eighty-nine dialysis patients performed the CDT. The CDT was scored by the methods of Rouleau et al. (RCS 10-point), Babins et al. (BCS 18-point), and the MoCA (MCS 3-point). Regression models were used to determine influencing demographic and dialysis variables. Scores were then correlated, and a combined factor analysis of scale components was done.
Females represented 44.6%, the mean (SD) age was 49.99 (15.49) years, and education duration was 10.29 (5.5) years. Dialysis vintage was 55.81 (62.91) months. The scores for the MCS, RCS, and BCS were 2.18 (1.08), 6.67 (3.07), and 11.8 (5.5), respectively, with significant correlation ( < 0.0001). In all scales, increasing age was associated with a lower score (each < 0.0001). The scores increased with increasing education (each < 0.0001). Diabetics had a lower score on both the BCS and MCS by 2.56 (SE 1.2) ( = 0.035) and 0.71 ( = 0.003) points, respectively. However, only age and years of education were significant in the multivariable analysis. In factor analysis, two shared factors appeared between the three scales: hand and number placement and the clock face.
Age and education influence the performance on the CDT, and factors diverged into executive and visuospatial components. The MCS is likely to yield useful information but should be interpreted as part of the MoCA.
画钟试验(CDT)常用于检测认知变化。已发表了多种不同长度的量表来评估其表现。本研究的目的是比较在非痴呆肾透析患者样本中,三种量表所测得的CDT表现,并确定影响表现的变量。这是一项在沙特国王大学医学城透析科进行的横断面研究。89名透析患者进行了画钟试验。画钟试验采用Rouleau等人的方法(RCS 10分制)、Babins等人的方法(BCS 18分制)和蒙特利尔认知评估量表(MoCA,MCS 3分制)进行评分。使用回归模型来确定影响人口统计学和透析的变量。然后对分数进行相关性分析,并对量表成分进行综合因子分析。
女性占44.6%,平均(标准差)年龄为49.99(15.49)岁,受教育年限为10.29(5.5)年。透析时间为55.81(62.91)个月。MCS、RCS和BCS的分数分别为2.18(1.08)、6.67(3.07)和11.8(5.5),具有显著相关性(<0.0001)。在所有量表中,年龄增加与分数降低相关(均<0.0001)。分数随着受教育程度的提高而增加(均<0.0001)。糖尿病患者在BCS和MCS上的分数分别降低2.56(标准误1.2)(P = 0.035)和0.71(P = 0.003)分。然而,在多变量分析中,只有年龄和受教育年限具有显著性。在因子分析中,三种量表之间出现了两个共同因子:指针和数字位置以及钟面。
年龄和教育程度影响画钟试验的表现,且因子分为执行和视觉空间成分。MCS可能会产生有用信息,但应作为MoCA的一部分进行解释。