Applied Neuromuscular Physiology Laboratory, Oklahoma State University, Stillwater, OK, USA; Laboratory of Applied Nutrition and Exercise Science, Oklahoma State University, Stillwater, OK, USA.
Applied Neuromuscular Physiology Laboratory, Oklahoma State University, Stillwater, OK, USA; Laboratory of Applied Nutrition and Exercise Science, Oklahoma State University, Stillwater, OK, USA.
Nutr Res. 2020 Nov;83:73-85. doi: 10.1016/j.nutres.2020.08.012. Epub 2020 Sep 2.
This study examined whether an acute bout of resistance exercise (RE) attenuated postprandial responses to a high fat meal (HFM) similarly in younger versus older adult men, and probed relationships among skeletal muscle mass (SMM), age, the metabolic load index (MLI) response, and the improvement in the MLI elicited by RE versus CON. Eleven younger (24 ± 4y) and 9 older (61 ± 5y) men completed RE or control (CON) the night prior to a HFM. Before and 1, 3, and 5 hours after the HFM, blood triglycerides (TG), glucose (GLU), MLI, and cholesterol concentrations were quantified. Following a 7 ± 1-day washout period, participants returned and completed the opposite condition. Independent of age, TGs were 32.1 ± 27.1 mg/dL and 52.7 ± 26.8 mg/dL lower in RE than CON at 3 and 5 hours, respectively. MLI was also 24.3 to 56.9 mg/dL lower in RE than CON from 1 to 5 hours post-meal independent of age. The TG and MLI area under the curves (AUCs) were 15% to 31% lower in RE than CON. The GLU response was greater in the older than younger men at 1 to 5 hours post-meal. Moreover, the average GLU response was 5.6 ± 2.5 mg/dL lower in RE versus CON and was inversely related to SMM across the sample (r = -0.615). However, age, volume, or SMM were not related to the MLI, nor to the improvement elicited by RE. Therefore, although the older men displayed a greater postprandial glucose response than the younger men, RE attenuated the postprandial metabolic response to a HFM similarly in younger and older men.
本研究旨在探究急性抗阻运动（RE）是否能同样减弱年轻和老年男性餐后对高脂肪餐（HFM）的反应，并探讨骨骼肌质量（SMM）、年龄、代谢负荷指数（MLI）反应以及 RE 与 CON 相比对 MLI 的改善之间的关系。11 名年轻男性（24±4 岁）和 9 名老年男性（61±5 岁）在 HFM 前一天晚上分别进行 RE 或对照（CON）。在 HFM 前、后 1、3 和 5 小时，检测血液甘油三酯（TG）、血糖（GLU）、MLI 和胆固醇浓度。经过 7±1 天的洗脱期后，参与者返回并完成相反的条件。与年龄无关，在 3 和 5 小时时，RE 组的 TG 比 CON 组低 32.1±27.1mg/dL 和 52.7±26.8mg/dL，而 MLI 也比 CON 组低 24.3-56.9mg/dL，从餐后 1 到 5 小时。TG 和 MLI 曲线下面积（AUC）在 RE 组比 CON 组低 15%-31%。在 HFM 后 1-5 小时，老年男性的 GLU 反应大于年轻男性。此外，RE 组的平均 GLU 反应比 CON 组低 5.6±2.5mg/dL，且在整个样本中与 SMM 呈负相关（r=-0.615）。然而，年龄、容量或 SMM 与 MLI 或 RE 引起的改善均无相关性。因此，尽管老年男性的餐后血糖反应大于年轻男性，但 RE 同样减弱了年轻和老年男性对 HFM 的餐后代谢反应。
