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1型多发性内分泌肿瘤（MEN1）伴肾结石：病例报告及文献复习

Multiple endocrine neoplasia type 1 (MEN1) presenting with renal stones: Case report and review.

作者信息

Ibrahim Mohamed N, Liem James, ElKady Ahmed

机构信息

Department of Diagnostic Radiology, Rotherham General Hospital, Moorgate Road, Rotherham, South Yorkshire S60 2UG, United Kingdom.

出版信息

Radiol Case Rep. 2020 Oct 3;15(12):2503-2509. doi: 10.1016/j.radcr.2020.09.037. eCollection 2020 Dec.

DOI:10.1016/j.radcr.2020.09.037
PMID:33033552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7533360/
Abstract

Multiple endocrine neoplasia type 1 (MEN1) is a complex, autosomal dominant inherited syndrome characterized by 3 different tumors (parathyroid, anterior pituitary, and pancreatic islet). The diagnosis is defined clinically by the presence of 2 or more primary tumors. We report the case of a 35 years old patient who presented with recurrent renal stones and imaging findings for MEN1. Computed tomography pancreas revealed a mass in the tail which was confirmed by magnetic resonance imaging. Ultrasound of her neck showed a mass on the left side and MIBI scan diagnosed a parathyroid adenoma which was later pathologically confirmed.

摘要

多发性内分泌腺瘤1型（MEN1）是一种复杂的常染色体显性遗传综合征，其特征为3种不同肿瘤（甲状旁腺、垂体前叶和胰岛）。临床诊断依据为存在2个或更多原发性肿瘤。我们报告1例35岁患者，该患者因复发性肾结石及MEN1的影像学表现前来就诊。胰腺计算机断层扫描显示胰尾有一肿块，磁共振成像证实了这一情况。其颈部超声显示左侧有一肿块，甲氧基异丁基异腈扫描诊断为甲状旁腺腺瘤，随后经病理证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/c9f75ec9bac0/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/6006d7b067f9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/983a2a4d88b6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/7ac9180a54d1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/63658ef2275e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/a0b84d133e5f/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/c9f75ec9bac0/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/6006d7b067f9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/983a2a4d88b6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/7ac9180a54d1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/63658ef2275e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/a0b84d133e5f/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a400/7533360/c9f75ec9bac0/gr6.jpg

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Assessing for Multiple Endocrine Neoplasia Type 1 in Patients Evaluated for Zollinger-Ellison Syndrome-Clues to a Safer Diagnostic Process.对因卓-艾综合征接受评估的患者进行1型多发性内分泌腺瘤病评估——安全诊断过程的线索
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