印度半城市小镇正常在校女大学生促甲状腺激素水平的估计：贡伯戈讷姆城乡流行病学研究 - KURES - 7
Estimation of Thyroid-Stimulating Hormone Level in Normal College Female Students in a Semi-Urban Indian Town: Kumbakonam Urban-Rural Epidemiological Study- KURES - 7.
作者信息
Suchitra M R, Shanthi T S, Parthasarathy Srinivasan
机构信息
Department of Biochemistry and Nutrition, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India.
Consultant Obstetrician, KRG Nursing Home, Department of Obstetrics and Gynaecology, Thanjavur, Tamil Nadu, India.
出版信息
Int J Prev Med. 2020 Jul 3;11:80. doi: 10.4103/ijpvm.IJPVM_406_19. eCollection 2020.
BACKGROUND
Subclinical hypothyroidism (SCH) is a biochemical disease which is characterized by elevated serum levels of thyroid stimulating hormone (TSH) with normal thyroid hormone levels. In an attempt to correct the disease at its entry point, we wished to find out the incidence of subclinical hypothyroidism in female college students in Kumbakonam, a semiurban town of India.
METHODS
Around 260 female college students who had no history of thyroid disease were screened for thyroid dysfunction by a TSH assay.
RESULTS
The mean age ± standard deviation was 18.72 ± 2.27 years. The mean TSH value was 3.98 mIU/mL. The incidence of abnormally high TSH values was around 11.5%. The number of such cases was 30 with low T3 values in six students. One had a value of 150 with no symptoms. Another student had a value of 0.15 and her T3-T4 profile was normal. All students were asymptomatic. None of the students had goiter.
CONCLUSIONS
In an unpublished but accepted study, we found an incidence of 3.5% in the school female children in the age group of 15-17. A sudden jump in the incidence is occurring in the age group of 18-22. This needs a workup of the causative factors and their possible correction.
背景
亚临床甲状腺功能减退症（SCH）是一种生化疾病，其特征是血清促甲状腺激素（TSH）水平升高而甲状腺激素水平正常。为了在疾病的起始点纠正该疾病，我们希望查明印度半城市小镇贡伯戈讷姆女大学生中亚临床甲状腺功能减退症的发病率。
方法
对约260名无甲状腺疾病史的女大学生进行促甲状腺激素检测以筛查甲状腺功能障碍。
结果
平均年龄±标准差为18.72±2.27岁。促甲状腺激素平均 值为3.98 mIU/mL。促甲状腺激素值异常高的发生率约为11.5%。此类病例有30例，6名学生的三碘甲状腺原氨酸（T3）值较低。1名学生的值为150但无症状。另一名学生的值为0.15，其T3 - 甲状腺素（T4）情况正常。所有学生均无症状。没有学生有甲状腺肿。
结论
在一项未发表但已被接受的研究中，我们发现15 - 17岁年龄段的在校女生发病率为3.5%。在18 - 22岁年龄段发病率突然上升。这需要对致病因素及其可能的纠正方法进行详细检查。
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