Klomparens Kara, Ding Yuchuan
Department of Neurosurgery, School of Medicine, Wayne State University, Detroit, MI, USA.
John D. Dingell VA Medical Center, Detroit, MI, USA.
Brain Circ. 2020 Jun 26;6(2):65-69. doi: 10.4103/bc.bc_18_20. eCollection 2020 Apr-Jun.
The purpose of this minireview is to outline the updates made on the association of Alzheimer's disease (AD) and brain injury. A review of the literature on this subject was conducted that included various aspects such as age of onset, severity of head trauma, and genetic influences. The results of this mini-review were that consistent associations of AD risk are seen when the severity of head trauma increases, the lag time decreases and when genetic links are present. Brain injury and AD have a complicated relationship that requires further studies to be fully understood.
本综述的目的是概述阿尔茨海默病（AD）与脑损伤之间关系的最新进展。对该主题的文献进行了综述，涵盖了发病年龄、头部创伤严重程度和遗传影响等各个方面。本综述的结果是，当头部创伤严重程度增加、延迟时间缩短以及存在遗传联系时，可观察到AD风险的一致关联。脑损伤与AD之间存在复杂的关系，需要进一步研究才能充分理解。
