van Miert A S
Tijdschr Diergeneeskd. 1987 Jul 15;112(14):836-43.
To begin with, a review paper on apomorphine, published by J.J. Hinze in 1875, is discussed. Subsequently, the development of pharmacology and rational pharmacotherapy is described. The progress of veterinary pharmacotherapy during the sixties and seventies is recalled on the basis of instances, and recent additions such as aditoprim, florphenicol and flumazenil are also referred to. Finally, the possibilities of biotechnology, particularly polypeptides which are produced using the recombinant DNA technique, such as interferons, interleukins and somatotropins (which are of interest from the point of view of zootechnics) are discussed. The recombinant DNA technique also makes it possible to synthesise receptor proteins, and thus offers new and interesting possibilities for future pharmacological studies.
首先，讨论了J.J.欣泽于1875年发表的一篇关于阿扑吗啡的综述论文。随后，描述了药理学和合理药物治疗的发展。根据实例回顾了六七十年代兽医药理学治疗的进展，还提到了最近添加的药物，如阿地普明、氟苯尼考和氟马西尼。最后，讨论了生物技术的可能性，特别是使用重组DNA技术生产的多肽，如干扰素、白细胞介素和生长激素（从动物饲养学的角度来看是有意义的）。重组DNA技术还使合成受体蛋白成为可能，从而为未来的药理学研究提供了新的有趣的可能性。
