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孟加拉国一家城市医院儿童腹泻的病因

The aetiology of diarrhoea in children at an urban hospital in Bangladesh.

作者信息

Moyenuddin M, Rahman K M, Sack D A

出版信息

Trans R Soc Trop Med Hyg. 1987;81(2):299-302. doi: 10.1016/0035-9203(87)90247-1.

DOI:10.1016/0035-9203(87)90247-1
PMID:3303485
Abstract

Enteric pathogens were studied in 104 cases with acute diarrhoea and in 74 age and sex matched concurrent controls. One or more pathogens were isolated from 59.1% of cases compared with 20.4% of controls (P less than 0.001). Single enteropathogens were detected in 33.7% and multiple enteropathogens in 25.4% of the cases. Enteropathogenic Escherichia coli (EPEC), Campylobacter jejuni, rotavirus, Vibrio cholerae non-O1 and enterotoxigenic Escherichia coli were the major pathogens detected. The high rate of isolation of EPEC from diarrhoea cases (23.1%) indicated a definite role for this pathogen in causing endemic diarrhoea in Bangladesh.

摘要

对104例急性腹泻患者以及74例年龄和性别匹配的同期对照者的肠道病原体进行了研究。59.1%的病例中分离出一种或多种病原体,而对照者中这一比例为20.4%(P<0.001)。33.7%的病例中检测到单一肠道病原体,25.4%的病例中检测到多种肠道病原体。致病性大肠杆菌(EPEC)、空肠弯曲菌、轮状病毒、非O1群霍乱弧菌和产肠毒素大肠杆菌是检测到的主要病原体。腹泻病例中EPEC的高分离率(23.1%)表明该病原体在孟加拉国地方性腹泻的发生中具有明确作用。

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