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[Morphological changes in the neuroendocrine system during experimental infection of animals with L-forms of group B Streptococcus].

作者信息

Khostikian N G, Vartazarian N D, Gorina L G

出版信息

Arkh Patol. 1987;49(5):64-70.

PMID:3304224
Abstract

White rats and mice were subjected to a single intraperitoneal inoculation with a stable L-form of Streptococcus B (strain 090). The hypothalamus, hypophysis and adrenal cortex of the animals were subsequently studied during one year. Progressive degenerative, inflammatory, necrotic and sclerotic changes found in the system hypothalamus-hypophysis-adrenals were due to the bacteria persistence in these organs leading to the disturbance of hormonal homeostasis and development of the system deficiency. There was also the tendency (in 6-12 months after the inoculation) to intensifying regeneration with partial recovery of the organs function.

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