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成人小肠结肠炎耶尔森菌感染的临床特征

Clinical aspects of infection with Yersinia enterocolitica in adults.

作者信息

Feeney G F, Kerlin P, Sampson J A

出版信息

Aust N Z J Med. 1987 Apr;17(2):216-9. doi: 10.1111/j.1445-5994.1987.tb00045.x.

DOI:10.1111/j.1445-5994.1987.tb00045.x
PMID:3304248
Abstract

Yersinia enterocolitica was isolated from the feces of 29 patients over a three-year period following the introduction of a selective culture medium. Y. enterocolitica was the third most common enteric pathogen after Campylobacter jejuni and Salmonella in this series of 3795 specimens from a predominantly adult population. The isolation rate of Y. enterocolitica was 0.9% and this represented 15.8% of positive cultures. The usual symptoms of Yersinia infection were diarrhea (93%) and abdominal pain (72%), often associated with tenderness in the right iliac fossa and fever. Fourteen patients required admission to hospital and four came to surgery for possible appendicitis. Acute terminal ileitis and mesenteric lymphadenitis were noted in each case. Two patients who were HLA-B27 positive had a reactive arthritis as their dominant complaint. In conclusion, Y. enterocolitica has emerged as a common cause of diarrhea in adults. It is an important cause of symptoms resembling those of acute appendicitis and is occasionally complicated by reactive arthritis.

摘要

在引入一种选择性培养基后的三年期间,从29名患者的粪便中分离出了小肠结肠炎耶尔森菌。在这一系列来自以成年人为主的3795份标本中,小肠结肠炎耶尔森菌是仅次于空肠弯曲菌和沙门氏菌的第三常见肠道病原体。小肠结肠炎耶尔森菌的分离率为0.9%,占阳性培养物的15.8%。耶尔森菌感染的常见症状为腹泻(93%)和腹痛(72%),常伴有右下腹压痛和发热。14名患者需要住院治疗,4名患者因可能的阑尾炎接受了手术。每例均发现急性末端回肠炎和肠系膜淋巴结炎。两名HLA - B27阳性患者以反应性关节炎为主要症状。总之,小肠结肠炎耶尔森菌已成为成人腹泻的常见病因。它是类似急性阑尾炎症状的重要病因,偶尔并发反应性关节炎。

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引用本文的文献

1
The invasin protein of Yersinia enterocolitica: internalization of invasin-bearing bacteria by eukaryotic cells is associated with reorganization of the cytoskeleton.小肠结肠炎耶尔森菌的侵袭蛋白:携带侵袭蛋白的细菌被真核细胞内化与细胞骨架的重组有关。
J Cell Biol. 1992 Jan;116(1):197-207. doi: 10.1083/jcb.116.1.197.
2
Polyarteritis associated with Yersinia enterocolitica infection.与小肠结肠炎耶尔森菌感染相关的多动脉炎。
Ann Rheum Dis. 1992 May;51(5):678-80. doi: 10.1136/ard.51.5.678.