Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.
Int J Cardiovasc Imaging. 2021 Mar;37(3):1085-1092. doi: 10.1007/s10554-020-02054-6. Epub 2020 Oct 12.
Coronary artery visibility on coronary CT angiography has rarely been investigated in young children with Kawasaki disease. This retrospective study was performed to quantitatively evaluate and compare coronary artery visibility with sufficient quality to measure it on coronary CT angiography among younger and older children with Kawasaki disease. Seventy-eight consecutive children with Kawasaki disease who underwent coronary CT angiography were divided into two groups: group 1 (age ≤ 6 years; n = 37) and group 2 (age > 6 years and < 18 years; n = 41). The visibility of the right coronary artery, left anterior descending artery, and left circumflex artery was quantitatively evaluated by dividing the length of the assessable coronary artery by the length of the corresponding groove, and compared between the two groups. The coronary artery visibility in group 1 was significantly lower than that in group 2 for the right coronary artery (77.8 ± 26.3% vs. 94.2 ± 13.6%, p < 0.002) and left anterior descending artery (54.8 ± 19.5% vs. 69.6 ± 21.3%, p < 0.003, but the difference was not significant for the left circumflex artery (43.7 ± 23.1% vs. 43.9 ± 26.7%, p > 0.9). In both groups, the visibility of the right coronary artery was the highest, followed by those of the left anterior descending artery and left circumflex artery. Compared with older children with Kawasaki disease, younger children with Kawasaki disease demonstrate significantly lower visibility of the right coronary artery and left anterior descending artery on coronary CT angiography. In contrast, the visibility of the left circumflex artery showed no significant difference between younger and older children with Kawasaki disease.
冠状动脉 CT 血管造影中冠状动脉的可视性在川崎病的幼儿中很少被研究。这项回顾性研究旨在定量评估和比较川崎病年幼和年长儿童中具有足够质量以进行测量的冠状动脉可视性。78 例连续接受冠状动脉 CT 血管造影的川崎病患儿分为两组:第 1 组(年龄≤6 岁;n=37)和第 2 组(年龄>6 岁且<18 岁;n=41)。通过将可评估的冠状动脉长度除以相应的沟长度,定量评估右冠状动脉、左前降支和左旋支的可视性,并比较两组之间的差异。第 1 组的右冠状动脉(77.8±26.3% vs. 94.2±13.6%,p<0.002)和左前降支(54.8±19.5% vs. 69.6±21.3%,p<0.003)的可视性明显低于第 2 组,但左回旋支的差异无统计学意义(43.7±23.1% vs. 43.9±26.7%,p>0.9)。在两组中,右冠状动脉的可视性最高,其次是左前降支和左回旋支。与年长的川崎病患儿相比,川崎病年幼患儿的冠状动脉 CT 血管造影显示右冠状动脉和左前降支的可视性明显较低。相比之下,左回旋支的可视性在川崎病年幼和年长患儿之间无显著差异。