Department of Cardiothoracic and Vascular Surgery, Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Department of Surgery, Faculty of Medicine, Damascus University, Damascus, Syria.
PLoS One. 2020 Oct 12;15(10):e0240144. doi: 10.1371/journal.pone.0240144. eCollection 2020.
Direct true lumen cannulation (DTLC) of the aorta is an alternative cardiopulmonary bypass cannulation technique in the context of type A acute aortic dissection (A-AAD). DTLC has been reported to be effective in restoring adequate perfusion to jeopardized organs. This study reports and compares operative outcomes with DTLC or alternative cannulation techniques in a large cohort of patients with A-AAD.
All patients who underwent surgery for A-AAD between January 2006 and January 2017 in Mainz university hospital were reviewed. The choice of cannulation technique was left to the operating surgeon, however DTLC was our preference in patients who were in state of shock or showed signs of tamponade or hypoperfusion, in cases of potential cerebral malperfusion, as well as in patients who were under resuscitation.
A total of 528 patients (63% males, mean age 64±13.8 years) underwent emergency surgery for A-AAD. The DTLC technique was used in 52.4% of patients. The DTLC group of patients had worse clinical status at the time of presentation with more shock, tamponade, true lumen collapse, cerebral and other malperfusion states. New neurologic events were diagnosed in around 8% of patients in each group following surgery, but there was a trend for quicker neurological recovery in the DTLC-group. Early mortality rates, short-term and long-term survival rates did not differ between the two groups.
DTLC is a safe cannulation technique that enables effective antegrade true lumen perfusion in complicated A-AAD scenarios, and is an advantageous addition to the aortic surgeons' armamentarium.
在急性 A 型主动脉夹层(A-AAD)的情况下,直接真腔插管(DTLC)是一种替代心肺转流的插管技术。已有报道称,DTLC 可有效恢复对危险器官的充分灌注。本研究报告了在一大组 A-AAD 患者中,采用 DTLC 或其他插管技术的手术结果,并对其进行了比较。
回顾了 2006 年 1 月至 2017 年 1 月期间在美因茨大学医院接受 A-AAD 手术的所有患者。插管技术的选择取决于手术医生,但在休克状态或出现填塞或灌注不足迹象、潜在脑灌注不良、以及正在复苏的患者中,我们倾向于使用 DTLC。
共有 528 名患者(63%为男性,平均年龄 64±13.8 岁)因 A-AAD 接受了紧急手术。52.4%的患者采用了 DTLC 技术。DTLC 组患者在就诊时的临床状况更差,休克、填塞、真腔塌陷、脑和其他灌注不良状态更多。两组患者术后均有 8%左右的患者新出现神经事件,但 DTLC 组的神经恢复更快。两组的早期死亡率、短期和长期生存率无差异。
DTLC 是一种安全的插管技术,可在复杂的 A-AAD 情况下实现有效的顺行真腔灌注,是主动脉外科医生的有利工具。