Backhouse C M, Blair S D, Savage A P, Walton J, McCollum C N
Br J Surg. 1987 Jul;74(7):626-7. doi: 10.1002/bjs.1800740732.
Fifty-six patients with chronic venous ulcers present for a mean of 2.4 years were randomized to either a new occlusive hydrocolloid dressing (Granuflex, Squibb Surgicare) or a porous non-adherent dressing (N A, Johnson and Johnson). In all patients, dressings were applied beneath a standard graduated compression bandage. There was no difference between the two groups, with complete healing in 21 out of 28 (75 per cent) of occlusive dressing patients and 22 out of 28 (78 per cent) with N A dressings by 12 weeks. Careful graduated compression bandaging achieves healing even in the majority of so-called resistant chronic venous ulcers; there was no additional benefit from applying occlusive dressings which tend to be expensive.
56例慢性静脉溃疡平均患病2.4年的患者被随机分为两组，分别使用新型封闭性水胶体敷料（Granuflex，施贵宝外科护理用品公司）或多孔性非粘性敷料（NA，强生公司）。所有患者均在标准分级压力绷带下使用敷料。两组之间无差异，到12周时，使用封闭性敷料的28例患者中有21例（75%）完全愈合，使用NA敷料的28例患者中有22例（78%）完全愈合。即使是大多数所谓难治性慢性静脉溃疡，仔细进行分级压力绷带包扎也能实现愈合；使用往往价格昂贵的封闭性敷料并无额外益处。
