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一项探索性的非随机研究,研究了在爱尔兰为寻求无家可归者支持性临时住宿服务(STA)的人群提供为期 3 个月的电子烟干预措施。

An exploratory non-randomized study of a 3-month electronic nicotine delivery system (ENDS) intervention with people accessing a homeless supported temporary accommodation service (STA) in Ireland.

机构信息

School of Health Science, Waterford Institute of Technology, Waterford, Ireland.

University of California San Francisco, San Francisco, USA.

出版信息

Harm Reduct J. 2020 Oct 12;17(1):73. doi: 10.1186/s12954-020-00406-y.

Abstract

BACKGROUND

Smoking is endemic amongst people accessing homeless services, and they are disproportionately affected by smoking-related diseases. This paper reports on the results of a 3-month small scale intervention which explored the efficacy, challenges and opportunities of using electronic nicotine delivery systems (ENDS) to support cessation of tobacco smoking with people accessing an Irish supported temporary accommodation (STA) homeless service. It considers the results of this intervention with reference to the balance of harms between the use of vaping to support smoking cessation and continued smoking.

METHODS

Twenty-three participants were recruited. Demographic data, carbon monoxide (CO) measurements, homelessness status and smoking history were recorded. Participants were given an ENDS device and two 10-ml bottles containing e-liquid available in several flavours and at several strengths. Participants could pick up new bottles on a weekly basis. At weeks 1, 4, 8 and 12, the Fagerström Test and Mood and Physical Symptoms Scale (MPSS) were administered.

RESULTS

Over 75% of the residents in the participating hostel were recruited (23/30). However, there was a substantial loss to follow-up (n = 14) as a result of data protection issues, the transient nature of the population of interest and non-compliance with the intervention. Self-reported reductions in cigarette consumption were found to be statistically significant (p < 0.001). However, reductions in carbon monoxide measurements were not statistically significant. Decreases in Fagerström Nicotine Dependence Test were statistically significant (p = 0.001), but decreases in MPSS "urge to smoke" and "strength of urges" composite scores were not. Reported side effects included coughing, runny nose, bleeding nose, slight sweating, dizziness, increased phlegm and a burning sensation at the back of the throat. Barriers to engagement were peer norms, vaping restrictions in accommodation and adverse life events. Positive effects reported included increased energy, less coughing, better breathing and financial benefits. An improvement in the domain "poor concentration" was also found to be statistically significant (p = 0.040).

CONCLUSION

ENDS-based interventions may be effective with this population. Future research should aim to improve follow-up, consider including behavioural components and monitor health effects in relation to ongoing concerns around risks and the balance of harms.

TRIAL REGISTRATION

Registered retrospectively ISRCTN14767579.

摘要

背景

在使用无家可归者服务的人群中,吸烟是普遍存在的,他们受到吸烟相关疾病的影响尤为严重。本文报告了一项为期 3 个月的小型干预研究的结果,该研究探索了使用电子尼古丁输送系统(ENDS)支持爱尔兰支持的临时住宿(STA)无家可归服务人群戒烟的效果、挑战和机会。本文考虑了这种干预措施的结果,参考了使用蒸气来支持戒烟和继续吸烟之间的危害平衡。

方法

招募了 23 名参与者。记录了人口统计学数据、一氧化碳(CO)测量值、无家可归状态和吸烟史。参与者被给予一个 ENDS 设备和两个装有不同口味和浓度的电子液体的 10 毫升瓶。参与者可以每周领取新的瓶子。在第 1、4、8 和 12 周时,进行了 Fagerström 测试和情绪和身体症状量表(MPSS)。

结果

参与宿舍的居民中有超过 75%(23/30)被招募。然而,由于数据保护问题、感兴趣人群的短暂性和对干预措施的不遵守,随访人员大量流失(n=14)。自我报告的香烟消耗量减少被发现具有统计学意义(p<0.001)。然而,一氧化碳测量值的减少没有统计学意义。Fagerström 尼古丁依赖测试的减少具有统计学意义(p=0.001),但 MPSS“吸烟冲动”和“冲动强度”综合评分的减少没有统计学意义。报告的副作用包括咳嗽、流鼻涕、流鼻血、轻微出汗、头晕、痰增多和喉咙后部烧灼感。参与的障碍包括同伴规范、住宿中对蒸气的限制和不良生活事件。报告的积极影响包括增加能量、减少咳嗽、改善呼吸和经济利益。在“注意力不集中”方面也发现了统计学上的改善(p=0.040)。

结论

基于 ENDS 的干预措施可能对这一人群有效。未来的研究应旨在提高随访率,考虑纳入行为成分,并监测与持续关注的风险和危害平衡有关的健康影响。

试验注册

回顾性注册 ISRCTN85155542。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0920/7549237/0f5d37f8b808/12954_2020_406_Fig1_HTML.jpg

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