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功能性二尖瓣反流行二尖瓣修复术的中期结果:一项回顾性研究。

Midterm results of mitral valve repair for atrial functional mitral regurgitation: a retrospective study.

机构信息

Division of Cardiovascular Surgery, Saitama Medical University International Medical Center, 1397-1, Yamane, Hidaka-shi, Saitama, 3501298, Japan.

出版信息

J Cardiothorac Surg. 2020 Oct 12;15(1):312. doi: 10.1186/s13019-020-01362-1.

Abstract

BACKGROUND

Annular dilation by left atrial remodeling is considered the main cause of atrial function mitral regurgitation. Although acceptable outcomes have been obtained using mitral ring annuloplasty alone for atrial functional mitral regurgitation, data assessing outcomes of this procedure are limited. Therefore, we aimed to assess midterm outcomes of mitral valve repair in patients with atrial functional mitral regurgitation.

METHODS

We retrospectively studied 40 patients (mean age: 69 ± 9 years) who had atrial fibrillation that persisted for > 1 year, preserved left ventricular ejection fraction of > 40%, and mitral valve repair for atrial functional mitral regurgitation. The mean clinical follow-up duration was 42 ± 24 months.

RESULTS

Mitral ring annuloplasty was performed for all patients. Additional repair including anterior mitral leaflet neochordoplasty was performed for 22 patients. Concomitant procedures included maze procedure in 20 patients and tricuspid ring annuloplasty in 31 patients. Follow-up echocardiography showed significant decreases in left atrial dimensions and left ventricular end-diastolic dimensions. Recurrent mitral regurgitation due to ring detachment or leaflet tethering was observed in five patients and was seen more frequently among those with preoperative left ventricular dilatation. Three patients without tricuspid ring annuloplasty or sinus rhythm recovery by maze procedure developed significant tricuspid regurgitation. Five patients who underwent the maze procedure showed sinus rhythm recovery. Rates of freedom from re-admission for heart failure at 1 and 5 years after surgery were 95 and 86%, respectively.

CONCLUSIONS

Mitral valve repair is not sufficient to prevent recurrent atrial functional mitral regurgitation in patients with preoperative left ventricular dilatation. Tricuspid ring annuloplasty may be required for long-term prevention of significant tricuspid regurgitation.

摘要

背景

左心房重构导致的环状扩张被认为是导致功能性二尖瓣反流的主要原因。尽管单独使用二尖瓣环成形术治疗功能性二尖瓣反流可获得可接受的结果,但评估该手术结果的数据有限。因此,我们旨在评估功能性二尖瓣反流患者行二尖瓣修复术的中期结果。

方法

我们回顾性研究了 40 名(平均年龄:69±9 岁)患者,这些患者均有持续>1 年的心房颤动、保留的左心室射血分数>40%,并因功能性二尖瓣反流而行二尖瓣修复术。平均临床随访时间为 42±24 个月。

结果

所有患者均行二尖瓣环成形术。22 名患者行二尖瓣前叶人工腱索成形术等附加修复。同期手术包括 20 名患者行迷宫手术和 31 名患者行三尖瓣环成形术。随访超声心动图显示左心房内径和左心室舒张末期内径显著减小。5 名患者因环分离或瓣叶牵拉导致复发性二尖瓣反流,术前左心室扩张患者中更常见。3 名未行三尖瓣环成形术或迷宫手术恢复窦性心律的患者出现严重三尖瓣反流。5 名行迷宫手术的患者恢复窦性心律。术后 1 年和 5 年无心力衰竭再入院的生存率分别为 95%和 86%。

结论

对于术前左心室扩张的患者,二尖瓣修复术不足以预防复发性功能性二尖瓣反流。对于长期预防严重三尖瓣反流,可能需要行三尖瓣环成形术。

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