Takahashi Yosuke, Abe Yukio, Sasaki Yasuyuki, Bito Yasuyuki, Morisaki Akimasa, Nishimura Shinsuke, Shibata Toshihiko
Department of Cardiovascular Surgery, Osaka City General Hospital, Osaka, Japan
Department of Cardiology, Osaka City General Hospital, Osaka, Japan.
Interact Cardiovasc Thorac Surg. 2015 Aug;21(2):163-8. doi: 10.1093/icvts/ivv119. Epub 2015 May 16.
Atrial functional mitral regurgitation (MR) has been recently described in patients with chronic atrial fibrillation (AF). However, the results of surgical mitral valve (MV) repair for this type of MR have not been comprehensively reported. Our study aimed to address this deficiency.
We retrospectively studied 10 chronic AF patients who underwent MV repair for atrial functional MR with normal left ventricular dimension and preserved left ventricular systolic function. All patients had chronic heart failure (HF) symptoms and at least one prior admission for HF complicated by severe MR.
Ring annuloplasty was performed in all patients; the median ring size was 26 mm (range, 26-30 mm). Concomitant tricuspid valve repair was undertaken in all patients. Preoperatively, left atrial (LA) diameter on the parasternal long-axis view, LA volume index and mitral annular diameter were 52 ± 9 mm, 72 ± 26 ml/m(2) and 33 ± 4 mm, respectively. There was no mortality and no re-admission due to HF during follow-up (range, 10-52 months). MR at the most recent examination was mild or improved in degree in all patients. The LA volume index decreased from the preoperative period, measuring 48 ± 17 ml/m(2) at the most recent period (P = 0.03). The New York Heart Association functional class dramatically improved from the preoperative period to the most recent period (from 3.0 ± 0.7 to 1.2 ± 0.4, P < 0.0001).
Our results suggest that MV repair leads to reductions in MR, LA size and HF symptoms, and that it may prevent future HF events in patients with atrial functional MR.
近期在慢性心房颤动(AF)患者中发现了心房功能性二尖瓣反流(MR)。然而,针对此类MR进行二尖瓣(MV)手术修复的结果尚未得到全面报道。我们的研究旨在填补这一空白。
我们回顾性研究了10例慢性AF患者,这些患者因心房功能性MR接受了MV修复,其左心室大小正常且左心室收缩功能保留。所有患者均有慢性心力衰竭(HF)症状,且至少有一次因HF合并严重MR而入院治疗。
所有患者均进行了瓣环成形术;瓣环大小中位数为26mm(范围为26 - 30mm)。所有患者均同时进行了三尖瓣修复。术前,胸骨旁长轴视图上的左心房(LA)直径、LA容积指数和二尖瓣环直径分别为52±9mm、72±26ml/m²和33±4mm。随访期间(范围为10 - 52个月)无死亡病例,也无因HF再次入院的情况。在最近一次检查中,所有患者的MR均为轻度或程度有所改善。LA容积指数较术前有所下降,最近一次测量为48±17ml/m²(P = 0.03)。纽约心脏协会心功能分级从术前到最近一次有显著改善(从3.0±0.7降至1.2±0.4,P < 0.0001)。
我们的结果表明,MV修复可导致MR、LA大小和HF症状减轻,并且可能预防心房功能性MR患者未来发生HF事件。