Herr H W
Cancer. 1987 Sep 15;60(6):1412-4. doi: 10.1002/1097-0142(19870915)60:6<1412::aid-cncr2820600640>3.0.co;2-e.
The linear-analogue self-assessment (LASA) technique was used to assess acute toxicity and other pertinent attributes relative to quality of life (QL) in patients with advanced testicular cancer who were entered into chemotherapy trials with either velban, Actinomycin-D, bleomycin, cisplatin, and cytoxan (VAB-6), etoposide and cisplatin (EP), or both regimens. Results showed significantly less nausea, vomiting, mucositis, and a earlier return to normal physical activity with EP versus VAB-6. The LASA method appears to be a valid measure of acute toxicity to chemotherapy in testicular cancer patients and provides objective QL information for patients entered into prospective clinical trials.
采用线性模拟自我评估（LASA）技术，对晚期睾丸癌患者在接受长春花碱、放线菌素-D、博来霉素、顺铂和环磷酰胺（VAB-6）、依托泊苷和顺铂（EP）或两种方案化疗试验时的急性毒性及其他与生活质量（QL）相关的属性进行评估。结果显示，与VAB-6相比，EP方案导致的恶心、呕吐、粘膜炎明显减少，身体活动恢复正常的时间更早。LASA方法似乎是衡量睾丸癌患者化疗急性毒性的有效手段，并为参加前瞻性临床试验的患者提供客观的生活质量信息。
