Samartsev V A, Gavrilov V A, Kuznetsova M V, Kuznetsova M P
Wagner Perm State Medical University, Perm, Russia.
Institute of Ecology and Genetics of Microorganisms, Perm, Russia.
Khirurgiia (Mosk). 2020(10):68-72. doi: 10.17116/hirurgia202010168.
To evaluate the role of various perioperative risk factors on the incidence of abdominal wound dehiscence.
A retrospective controlled randomized trial of the risk factors of abdominal wound dehiscence was conducted in 62 patients for the period 2013- 2018. The research was performed at the Perm City Clinical Hospital No. 4. All patients were divided into two groups: the main one (=31) with abdominal wound dehiscence in early postoperative period and the control group (=31) without this event. Both groups were comparable by gender, age and surgical abdominal diseases. Between-group differences in numerical indicators were analyzed using Mann-Whitney U-test, qualitative variables were analyzed using contingency tables. Differences were significant at -value <0.05.
Incidence of abdominal wound dehiscence was similar in patients who admitted in emergency and elective fashion (=0.54). Anemia upon admission (=0.71), diabetes mellitus type 2 (=1.00), COPD (=0.13) and obesity (=0.76) were not significant predictors of abdominal wound dehiscence. There were significant between-group differences in CRP level (=0.04). Among intraoperative risk factors, duration of surgery (=0.78), surgical approach (=1.00), aponeurosis suturing technique (=0.39) and stoma (=0.71) did not significantly affect the incidence of abdominal wound dehiscence. In early postoperative period, abdominal wound dehiscence correlated with peritonitis (=0.04), SSI (<0.01) and redo laparotomy (=0.02).
Despite the variety of pre-, intra- and postoperative risk factors, only infectious postoperative complications (SSI, peritonitis) and redo surgical interventions influenced the development of abdominal wound dehiscence. Thus, the concept of abdominal wound dehiscence prevention should be inextricably associated with the concept of prevention of postoperative infectious complications from the abdominal wall and abdominal cavity.
评估各种围手术期危险因素对腹部伤口裂开发生率的影响。
对2013年至2018年期间62例患者进行腹部伤口裂开危险因素的回顾性对照随机试验。研究在彼尔姆市第4临床医院进行。所有患者分为两组:主要组(=31例)为术后早期出现腹部伤口裂开的患者,对照组(=31例)未发生该事件。两组在性别、年龄和腹部外科疾病方面具有可比性。数值指标的组间差异采用曼-惠特尼U检验分析,定性变量采用列联表分析。差异在P值<0.05时具有统计学意义。
急诊入院和择期入院患者的腹部伤口裂开发生率相似(=0.54)。入院时贫血(=0.71)、2型糖尿病(=1.00)、慢性阻塞性肺疾病(=0.13)和肥胖(=0.76)不是腹部伤口裂开的显著预测因素。两组间CRP水平存在显著差异(=0.04)。在术中危险因素中,手术时间(=0.78)、手术入路(=1.00)、腱膜缝合技术(=0.39)和造口(=0.71)对腹部伤口裂开发生率无显著影响。在术后早期,腹部伤口裂开与腹膜炎(=0.04)、手术部位感染(<0.01)和再次剖腹手术(=0.02)相关。
尽管存在多种术前、术中和术后危险因素,但只有术后感染性并发症(手术部位感染、腹膜炎)和再次手术干预会影响腹部伤口裂开的发生。因此,腹部伤口裂开预防的概念应与腹壁和腹腔术后感染性并发症的预防概念紧密相关。