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[腹壁前部巨大局限性淋巴水肿]

[Massive localized lymphedema of anterior abdominal wall].

作者信息

Gogiya B Sh, Alyautdinov R R, Karmazanovsky G G, Kalinin D V, Glotov A V, Leonova A I

机构信息

Vishnevsky National Medical Research Center of Surgery, Moscow, Russia.

出版信息

Khirurgiia (Mosk). 2020(10):116-122. doi: 10.17116/hirurgia2020101116.

DOI:10.17116/hirurgia2020101116
PMID:33047595
Abstract

Massive localized lymphedema (MLL) is a rare disease observed in people with morbid obesity. MLL is easily confused with soft tissue sarcoma. Therefore, MLL is sometimes called as pseudosarcoma in the literature. MLL was initially described by G. Farshid and S. Weiss in 1998. However, etiology of MLL is still unknown despite certain relationships with injuries, operations and hypothyroidism. Since the term «MLL» was introduced only 20 years ago, there are no reliable statistical data on the prevalence of MLL. According to the World Health Organization data (2016), 13% of the adult world population are obese. Therefore, the risk of MLL is increased in these people. Thigh is the most common site of lesion. Abdominal wall lesion is rare and can cause diagnostic difficulties due to large dimensions and appearance. We report a 50-year-old obese woman with MLL of anterior abdominal wall. She experienced discomfort while walking and sleeping due to giant MLL of anterior abdominal wall that significantly reduced quality of life. Removal of MLL (weight 22160 g) was followed by favorable cosmetic and functional outcome. Analysis of differences between MLL and soft tissue sarcoma in the era of «obesity epidemic» is valuable for correct diagnosis and treatment of this rare complication. This report is the first case of MLL, registered in Russia. In our opinion, this is associated with insufficient awareness of physicians about this complication of obesity. We hope our observation will help clinicians to identify and treat this complication.

摘要

巨大局限性淋巴水肿(MLL)是一种在病态肥胖人群中观察到的罕见疾病。MLL很容易与软组织肉瘤混淆。因此,在文献中MLL有时被称为假肉瘤。MLL最初由G.法希德和S.韦斯于1998年描述。然而,尽管MLL与损伤、手术和甲状腺功能减退有一定关系,但其病因仍然不明。由于“MLL”这一术语20年前才被提出,目前尚无关于MLL患病率的可靠统计数据。根据世界卫生组织(2016年)的数据,全球13%的成年人口肥胖。因此,这些人的MLL风险增加。大腿是最常见的病变部位。腹壁病变罕见,由于尺寸大且外观特殊,可能导致诊断困难。我们报告一例50岁肥胖女性,患有前腹壁MLL。由于前腹壁巨大MLL,她在行走和睡眠时感到不适,严重降低了生活质量。切除MLL(重量22160克)后,获得了良好的美容和功能效果。在“肥胖流行”时代分析MLL与软组织肉瘤之间的差异,对于正确诊断和治疗这种罕见并发症具有重要价值。本报告是俄罗斯登记的首例MLL病例。我们认为,这与医生对这种肥胖并发症认识不足有关。我们希望我们的观察结果能帮助临床医生识别和治疗这种并发症。

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