Edah J O, Goar S G, Odoh G, Lawal B, Dayom P S, Sunday Z F, Sawa I F, Obi C V, Ochigbo E E, Puepet F H
Department of Internal Medicine, Jos University Teaching Hospital, Lamingo; Department of Medicine, University of Jos, Jos, Plateau State, Nigeria.
Psychiatry, Jos University Teaching Hospital, Lamingo; Psychiatry, University of Jos, Jos, Plateau State, Nigeria.
Niger J Clin Pract. 2020 Oct;23(10):1431-1436. doi: 10.4103/njcp.njcp_155_20.
Diabetes mellitus (DM) and depression are common chronic disease states of public health importance with huge burden and the potential to impact many aspects of life. They are said to be related though this relationship is not fully understood. The presence of depression among patients with DM is associated with poor glycemic control, complications, and poor self-care.
This was a descriptive cross-sectional study conducted at the Diabetes Clinic of the Jos University Teaching Hospital. Three hundred and ten (310) patients with diabetes mellitus were recruited consecutively. The depression module of the Mini International Neuropsychiatric Interview (M.I.N.I.) version 5.0 was used to ascertain depression among these patients. Other demographic data were obtained using a questionnaire. Blood pressure, weight, and height were also measured and the body mass index (BMI) calculated.
One hundred and eighty four (59.35%) of the study population were females and the mean age (SD) of the study population was 54 ± 12 years. The mean age (SD) of the females was 53 ± 11 years and that of the males was 54 ± 12 years with no significant statistical difference (P = 0.35). Two hundred and forty nine (80.32%) of the study population were urban dwellers with 140 (45.16%) earning less than N500, 000 (794 USD) yearly. Current major depression was found in 35 (11.3%) patients, among whom 7 (2.3%) had recurrent depression. The presence of DM complications (OR: 3.50, 95% CI 1.16-10.61) and a positive family history of depression (OR: 4.03, 95% CI 1.32-12.29) were found to be correlates of current major depression.
The prevalence of current major depression among patients with diabetes mellitus in this study is high. We recommend that all patients with DM should be screened for depression and treated appropriately to reduce its consequences.
糖尿病(DM)和抑郁症是具有公共卫生重要性的常见慢性病状态,负担巨大且有可能影响生活的许多方面。尽管这种关系尚未完全明了,但据说二者有关联。糖尿病患者中存在抑郁症与血糖控制不佳、并发症及自我护理差有关。
这是一项在乔斯大学教学医院糖尿病诊所进行的描述性横断面研究。连续招募了310例糖尿病患者。使用迷你国际神经精神访谈(M.I.N.I.)第5.0版的抑郁模块来确定这些患者是否患有抑郁症。使用问卷获取其他人口统计学数据。还测量了血压、体重和身高,并计算了体重指数(BMI)。
研究人群中184例(59.35%)为女性,研究人群的平均年龄(标准差)为54±12岁。女性的平均年龄(标准差)为53±11岁,男性为54±12岁,无显著统计学差异(P = 0.35)。研究人群中249例(80.32%)为城市居民,其中140例(45.16%)年收入低于50万奈拉(794美元)。35例(11.3%)患者存在当前重度抑郁症,其中7例(2.3%)有复发性抑郁症。发现糖尿病并发症的存在(比值比:3.50,95%置信区间1.16 - 10.61)和抑郁症家族史阳性(比值比:4.03,95%置信区间1.32 - 12.29)与当前重度抑郁症相关。
本研究中糖尿病患者当前重度抑郁症的患病率较高。我们建议对所有糖尿病患者进行抑郁症筛查并给予适当治疗,以减轻其后果。