From the Geriatrics Service, Section of Hospice and Palliative Care, Southeast Louisiana Veterans Health Care System, New Orleans, Louisiana (AEL, JM, RVB, RR, AMR); School of Medicine, Tulane University, New Orleans, Louisiana (AEL, RVB); South Central Mental Illness Research, Education, and Clinical Center (MIRECC), New Orleans, Louisiana (AMR); and School of Medicine, Louisiana State University, New Orleans, Louisiana (AMR).
Am J Phys Med Rehabil. 2021 Jan 1;100(1):34-38. doi: 10.1097/PHM.0000000000001614.
The aim of this study was to examine the impact of demographics, preexisting medical conditions, and in-hospital complications of COVID-19 infection on functional status at discharge.
A retrospective chart review was conducted on 119 patients hospitalized for COVID-19 infection between March 1, 2020, and April 20, 2020. Demographics, preexisting medical conditions, and newly diagnosed COVID-19 complications were collected from electronic medical records and entered in a deidentified database.
The primary outcome was functional status at discharge, as measured by independence in activities of daily living.
Older age, respiratory failure, cardiac conditions, and thromboembolic complications all made a statistically significant contribution to functional dependence at discharge, with thromboembolic complications evincing the strongest association (odds ratio, 25.58).
New diagnosis of thrombosis during COVID-19 hospitalization, a measure of COVID-19 disease severity, was the factor most associated with dependence in activities of daily living at discharge. Interestingly, preexisting conditions including hypertension, severe obesity, lung disease, and diabetes did not correlate with dependent functional status at discharge.
本研究旨在探讨 COVID-19 感染患者的人口统计学、既往医疗状况和住院并发症对出院时功能状态的影响。
对 2020 年 3 月 1 日至 4 月 20 日期间因 COVID-19 感染住院的 119 名患者进行了回顾性图表审查。从电子病历中收集了人口统计学、既往医疗状况和新诊断的 COVID-19 并发症，并将其输入到一个匿名数据库中。
主要结局是出院时的功能状态，通过日常生活活动的独立性来衡量。
年龄较大、呼吸衰竭、心脏状况和血栓栓塞并发症都与出院时的功能依赖有统计学显著相关性，血栓栓塞并发症的相关性最强（优势比，25.58）。
COVID-19 住院期间新诊断的血栓形成是 COVID-19 疾病严重程度的一个指标，与出院时日常生活活动的依赖程度最相关。有趣的是，包括高血压、严重肥胖、肺部疾病和糖尿病在内的既往疾病与出院时功能依赖状态不相关。
