Bignold L P
Experientia. 1987 Aug 15;43(8):860-8. doi: 10.1007/BF01951643.
Diverse cell types, including Amoebae, leukocytes, embryonic cells and tumour cells move about on solid surfaces to accomplish such activities as feeding, bacterial destruction, embryological development and metastasis. Theories of the mechanism of this movement are reviewed and a model is proposed which invokes the existence of specific, laterally mobile, transmembranous structures in the cell membrane, which are reversibly adhesive for both the contractile apparatus of the cell internally, and the substratum externally. By this model, the movement of all these cell types can be explained.
包括变形虫、白细胞、胚胎细胞和肿瘤细胞在内的多种细胞类型在固体表面移动，以完成诸如进食、细菌破坏、胚胎发育和转移等活动。本文综述了这种运动机制的理论，并提出了一个模型，该模型认为细胞膜中存在特定的、侧向移动的跨膜结构，这些结构对细胞内部的收缩装置和外部的基质具有可逆粘附性。通过这个模型，可以解释所有这些细胞类型的运动。
