Department of Cardiology, The Royal Melbourne Hospital, Melbourne Health, Melbourne, Victoria, Australia.
Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia, Departments of Neurology and Medicine, The Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia, Department of Neurology, Alfred Health, Melbourne, Victoria, Australia.
Epileptic Disord. 2020 Oct 1;22(5):669-672. doi: 10.1684/epd.2020.1207.
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy-related mortality. Its mechanisms remain incompletely understood. Post-ictal arrhythmias rather than ictal arrhythmias appear to be associated with an increased risk of SUDEP. Only a handful of individuals with epilepsy who have survived ventricular arrhythmias post seizure (near-SUDEP) are reported in the literature. We report a case of ventricular fibrillation following a first-ever unprovoked seizure in a patient without epilepsy, in whom a sinus rhythm was restored following cardioversion. A defibrillator was subsequently implanted. Our case suggests that even first seizures might account for some of the many cases of unexplained ventricular fibrillation or sudden cardiac death.
癫痫性猝死（SUDEP）是癫痫相关死亡的主要原因。其机制仍不完全清楚。癫痫发作后心律失常而不是癫痫发作时的心律失常似乎与 SUDEP 风险增加有关。文献中仅报道了少数癫痫患者在癫痫发作后幸存室性心律失常（近 SUDEP）的病例。我们报告了一例无癫痫患者首次无诱因发作后出现心室颤动的病例，该患者在电复律后恢复窦性心律。随后植入了除颤器。我们的病例表明，即使是首次发作也可能导致许多不明原因的心室颤动或心源性猝死的发生。
