Zaletel Benda Polona, Vratanar Bor, Petrovski Goran, Gavrić Ana Uršula, Matović Katja, Gornik Ana, Vergot Katarina, Lumi Anila, Lumi Xhevat
Eye Hospital, University Medical Centre Ljubljana, Grablovičeva 46, 1000 Ljubljana, Slovenia.
Institute for Biostatistics and Medical Informatics, Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000 Ljubljana, Slovenia.
J Clin Med. 2020 Oct 12;9(10):3251. doi: 10.3390/jcm9103251.
Pars plana vitrectomy (PPV) is a surgical approach mainly chosen for complex rhegmatogenous retinal detachment (RRD) repair with highly variable functional results. The aim of this analysis was to evaluate the impact of preoperative factors and postoperative optical coherence tomography (OCT) macular findings on the functional outcome of patients undergoing primary PPV for RRD. A retrospective analysis was performed on 88 eyes of 88 patients with complex RRD managed by PPV. A swept source OCT was used to obtain images at the postoperative visit at least 6 months after PPV. Hierarchical linear regression model was used to evaluate the influence of preoperative factors related to patient, ocular clinical and postoperative OCT macular findings on functional outcomes of PPV for RRD. Duration of symptoms ( = 0.031) and discontinuity of the ellipsoid zone (EZ) on OCT ( = 0.024) showed statistically significant negative correlation, while preoperative best-corrected visual acuity (BCVA; < 0.001) showed statistically significant positive correlation to postoperative BCVA. Preoperative BCVA and duration of symptoms can be used as prognostic factors for visual outcome in patients undergoing PPV for RRD. Discontinuity of the EZ was the only postoperative OCT variable related to worse postoperative visual outcome.
玻璃体切割术（PPV）是一种主要用于修复复杂孔源性视网膜脱离（RRD）的手术方法，其功能结果差异很大。本分析的目的是评估术前因素和术后光学相干断层扫描（OCT）黄斑区检查结果对接受原发性PPV治疗RRD患者功能结局的影响。对88例接受PPV治疗的复杂RRD患者的88只眼进行了回顾性分析。采用扫频源OCT在PPV术后至少6个月的随访中获取图像。采用分层线性回归模型评估与患者、眼部临床情况及术后OCT黄斑区检查结果相关的术前因素对PPV治疗RRD功能结局的影响。症状持续时间（=0.031）和OCT上椭圆体带（EZ）的连续性中断（=0.024）显示出统计学上的显著负相关，而术前最佳矫正视力（BCVA；<0.001）与术后BCVA显示出统计学上的显著正相关。术前BCVA和症状持续时间可作为接受PPV治疗RRD患者视力预后的预测因素。EZ的连续性中断是与术后视力较差相关的唯一术后OCT变量。
