Zhang Xian, Chen Liting, Wei Jia, Zhou Jianfeng, Cao Yang, Wang Gaoxiang
Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, People's Republic of China.
Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, People's Republic of China.
Infect Drug Resist. 2020 Sep 24;13:3267-3271. doi: 10.2147/IDR.S261304. eCollection 2020.
There is increasing evidence indicating that considerable fractions of cases of SARS-CoV-2 infection are asymptomatic. We traced three asymptomatic clusters to investigate the infectivity of subclinical cases of coronavirus disease 2019 (COVID-19).
Three medical staff who were asymptomatic were diagnosed with coronavirus disease 2019 by serological tests. Their close contacts were systematically evaluated based on COVID-19-related symptoms, nucleic acid tests, serological tests, and chest computed tomography (CT) as needed to determine if they were infected by SARS-CoV-2.
None of the staff's close contacts, including 10 family members, were infected by the indexes, even though no protective measures were taken.
The infectivity of asymptomatic subclinical infection patients of coronavirus disease 2019 seems to be low.
越来越多的证据表明，相当一部分严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）感染病例是无症状的。我们追踪了三个无症状聚集性病例，以调查2019冠状病毒病（COVID-19）亚临床病例的传染性。
三名无症状医务人员经血清学检测确诊为2019冠状病毒病。根据COVID-19相关症状、核酸检测、血清学检测以及必要时的胸部计算机断层扫描（CT），对他们的密切接触者进行系统评估，以确定他们是否感染了SARS-CoV-2。
尽管未采取防护措施，但包括10名家庭成员在内的所有密切接触者均未被这些指数病例感染。
2019冠状病毒病无症状亚临床感染患者的传染性似乎较低。
