Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital, Wuhan University, Wuhan, 430071 Hubei, China.
Department of Orthopedic, The First College of Clinical Medical Science, China Three Gorges University& Yichang Central People's Hospital, Yichang, Hubei, China.
Biomed Res Int. 2020 Oct 5;2020:8469560. doi: 10.1155/2020/8469560. eCollection 2020.
To understand how to implement proactive prevention measures among healthcare professionals for preventing potential nosocomial infection.
91 healthcare professionals confirmed with the COVID-19 infection were collected, and clinical characteristics and epidemiological data were evaluated.
Among the cases, 77 cases (84.6%) were confirmed by the viral nucleic acid test, and the other 14 cases were diagnosed by the clinical investigation. Ground glass opacity and bilateral shadows distribution were observed in 78 cases (85.6%). 56 cases (61.5%) were admitted into Zhongnan Hospital and subjected to antiviral treatment. 73 of a total of 91 cases (80.2%) with a median incubation period of 3 days (IQR, 2 to 6) reported close contact history with patients with the COVID-19 infection. The most common symptoms at the onset of illness were fever (66 cases, 72.5%) and cough (54 cases, 59.3%). The initial positive rate of the CT scan and RT-PCR assay were 84.6% and 48.4%, respectively ( < 0.01). There were 50 cases occurred during the early stage (before Jan 20, 2020), whereas 41 cases occurred at a late stage (after Jan 20, 2020). In the early stage, the most common route of exposure to COVID-19 was via direct care in the absence of any invasive procedure. By contrast, 37 healthcare professionals infected with COVID-19 in the late stage were confirmed to have been exposed via aerosol-generating procedures.
Identification of the asymptomatic individuals in healthcare settings and prompt response when a suspicious case is considered may render effective control of the nosocomial infection during this pandemic.
了解如何在医护人员中实施主动预防措施，以预防潜在的医院感染。
收集了 91 例经新冠病毒感染确诊的医护人员，评估其临床特征和流行病学数据。
在这些病例中，77 例（84.6%）经病毒核酸检测确诊，其余 14 例由临床调查诊断。78 例（85.6%）观察到磨玻璃影和双侧阴影分布。56 例（61.5%）收入中南医院接受抗病毒治疗。91 例中共有 73 例（80.2%）中位潜伏期为 3 天（IQR，2~6），报告与新冠病毒感染患者有密切接触史。发病时最常见的症状是发热（66 例，72.5%）和咳嗽（54 例，59.3%）。CT 扫描和 RT-PCR 检测的初始阳性率分别为 84.6%和 48.4%（<0.01）。50 例发生在早期（2020 年 1 月 20 日前），41 例发生在晚期（2020 年 1 月 20 日后）。在早期，接触新冠病毒最常见的途径是在没有任何侵入性操作的情况下直接护理，而晚期有 37 名医护人员经确认是通过产生气溶胶的程序感染了新冠病毒。
在大流行期间，识别医疗机构中的无症状个体并在怀疑病例时迅速做出反应，可能会有效地控制医院感染。
