Department of Pathology and Laboratory Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
American Red Cross, Columbus, Ohio, USA.
J Clin Apher. 2021 Feb;36(1):161-176. doi: 10.1002/jca.21850. Epub 2020 Oct 16.
Therapeutic plasma exchange is used to treat neurological diseases in the pediatric population. Since its first use in pediatric patients with hepatic coma in the form of manual whole blood exchange, therapeutic plasma exchange has been increasingly used to treat these disorders of the nervous system. This expansion is a result of improved techniques and apheresis instruments suitable for small children, as well as the recognition of its applicability to many diseases in the pediatric population. This review provides a historical overview of the use of therapeutic apheresis in children and highlights the most common applications for therapeutic plasma exchange to treat neurological disorders in children.
治疗性血浆置换用于治疗儿科人群的神经疾病。自最初将其用于肝昏迷的儿科患者的全血手动置换以来，治疗性血浆置换已越来越多地用于治疗这些神经系统疾病。这种扩展是由于改进的技术和适合小儿的血液分离仪器，以及认识到其适用于儿科人群中的许多疾病所致。本文回顾了治疗性血液分离在儿童中的应用，并重点介绍了治疗性血浆置换治疗儿童神经疾病的最常见应用。
