Department of Urology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, Turkey.
Int J Clin Pract. 2021 Mar;75(3):e13753. doi: 10.1111/ijcp.13753. Epub 2020 Nov 9.
This study aims to analyse the novel Coronavirus disease- (COVID-19) related testicular pain in hospitalised patients because of COVID-19 and to review as an aetiological factor for epididymitis, orchitis or both.
A total of 91 patients were included in the study. A questionnaire was formed for the questioning of testicular pain or epididymo-orchitis in patients with COVID-19. Demographics and past medical history was also recorded. Patients' neutrophil and lymphocyte counts, neutrophil-lymphocyte ratios (NLR), C-reactive protein (CRP) levels and D-dimer values were recorded. Patients with COVID-19 were divided into two groups according to absence or presence of testicular pain or epididymo-orchitis as group 1 and group 2. All results were compared for both groups.
The median age of patients was similar in both groups. Testicular pain was occurred in 10.98% of the patients. Clinical presentation of epididymo-orchitis was diagnosed in only one patient. No statistically significant difference was reported in terms of patients' age, levels of CRP and D-Dimer or NLR and results of questionnaire form queries between the two groups (P > .05).
Testicular pain was observed more frequently in hospitalised COVID-19 cases. While no inflammation marker which is related to predict of testicular pain or epididymo-orchitis was found in patients with COVID-19.
本研究旨在分析因 COVID-19 住院的患者中与新型冠状病毒病（COVID-19）相关的睾丸痛，并将其作为睾丸炎、附睾炎或两者同时发生的病因进行综述。
共纳入 91 例患者。我们为 COVID-19 患者设计了一份问卷，用于询问睾丸痛或附睾睾丸炎的情况。还记录了患者的人口统计学和既往病史。记录了患者的中性粒细胞和淋巴细胞计数、中性粒细胞-淋巴细胞比值（NLR）、C 反应蛋白（CRP）水平和 D-二聚体值。根据是否存在睾丸痛或附睾睾丸炎，将 COVID-19 患者分为两组，即第 1 组和第 2 组。比较两组所有结果。
两组患者的中位年龄相似。10.98%的患者出现睾丸痛。仅 1 例患者被诊断为附睾睾丸炎。两组间患者年龄、CRP 和 D-二聚体或 NLR 水平以及问卷查询结果无统计学差异（P>.05）。
COVID-19 住院患者中更常观察到睾丸痛。虽然在 COVID-19 患者中未发现与睾丸痛或附睾睾丸炎相关的预测炎症标志物。
