极低出生体重和超低出生体重儿的脂肪分布：一项队列研究
Fat Distribution among Children Born Extremely Low Birth Weight and Very Low Birth Weight: A Cohort Study.
作者信息
Alves Susi Araújo, Cavalcante Emanuela Virginia, Melo Narjara Tiane, Lima Ana Corina, E Silva Eduardo Just, de Lima Geisy Maria, Figueiroa Jose Natal, Alves João Guilherme
机构信息
Department of Pediatrics, Faculdade Pernambucana de Saúde (FPS), Recife, Brazil.
Department of Radiology, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil.
出版信息
Child Obes. 2020 Dec;16(8):549-553. doi: 10.1089/chi.2020.0186. Epub 2020 Oct 16.
Fat distribution is associated with chronic diseases and birth weight may influence fat distribution throughout life. Our aim was to compare fat distribution in children born extremely low birth weight (ELBW) and very low birth weight (VLBW). This retrospective cohort study evaluated children born ELBW and VLBW around the 7th year of life. Fat distribution was assessed by ultrasonography measurements of abdominal subcutaneous and visceral fat thickness. Multiple linear regression analysis was performed. We studied 63 children. Visceral fat thickness but not subcutaneous fat thickness was significantly increased in children born ELBW compared with children born VLBW, respectively, 3.13 (±1.08) versus 1.86 (±0.76) mm. This result remained after adjustment for age, gender, and BMI; adjusted coefficient 0.118, 95% confidence interval 0.009-0.227, = 0.034. Children born ELBW seem to have increased visceral fat thickness compared with children born VLBW.
脂肪分布与慢性疾病相关，出生体重可能会影响一生的脂肪分布。我们的目的是比较极低出生体重（ELBW）和超低出生体重（VLBW）儿童的脂肪分布情况。这项回顾性队列研究评估了出生时为ELBW和VLBW的儿童在7岁左右时的情况。通过超声测量腹部皮下和内脏脂肪厚度来评估脂肪分布。进行了多元线性回归分析。我们研究了63名儿童。与出生时为VLBW的儿童相比，出生时为ELBW的儿童内脏脂肪厚度显著增加，分别为3.13（±1.08）毫米和1.86（±0.76）毫米，而皮下脂肪厚度无显著差异。在对年龄、性别和体重指数进行调整后，这一结果仍然成立；调整系数为0.118，95%置信区间为0.009 - 0.227，P = 0.034。与出生时为VLBW的儿童相比，出生时为ELBW的儿童似乎内脏脂肪厚度增加。
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